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JAK3 INHIBITOR VI

Product Name
JAK3 INHIBITOR VI
CAS No.
856436-16-3
Chemical Name
JAK3 INHIBITOR VI
Synonyms
JI6;JAK3 INHIBITOR VI
CBNumber
CB3787012
Molecular Formula
C19H17N3O4S
Formula Weight
383.42098
MOL File
856436-16-3.mol
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JAK3 INHIBITOR VI Property

storage temp. 
+2C to +8C
form 
Yellow solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
420126
Product name
JAK3 Inhibitor VI - CAS 856436-16-3 - Calbiochem
Packaging
5MG
Price
$195
Updated
2023/06/20
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JAK3 INHIBITOR VI Chemical Properties,Usage,Production

General Description

A cell-permeable, potent, and reversible inhibitor of Janus kinase 3 (JAK3) (IC50 = 27 nM). Reported to bind to the enzyme active site and prevent IL-2-induced phosphorylation of JAK3 and STAT5. Also reported to inhibit IL-2-induced cell proliferation (IC50 = 760 nM for murine CTLL cells and 250 nM for human T-cells). Shown to alleviate oxazolone-induced ear edema in mice with an efficacy comparable to Dexamethasone (Cat. No. 265005) and displays ~16-fold greater selectivity over JAK2.

Biochem/physiol Actions

Cell permeable: yes

JAK3 INHIBITOR VI Preparation Products And Raw materials

Raw materials

Preparation Products

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JAK3 INHIBITOR VI Suppliers

China 6 United States 2 Global 8
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
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80
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
3501
Advantage
55
Beijing Biocreative Technology Co., Ltd.
Tel
15522676233
Email
3007606172@qq.com
Country
China
ProdList
1249
Advantage
58

856436-16-3, JAK3 INHIBITOR VIRelated Search:


  • JAK3 INHIBITOR VI
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