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JAK3 INHIBITOR VI

Product Name
JAK3 INHIBITOR VI
CAS No.
856436-16-3
Chemical Name
JAK3 INHIBITOR VI
Synonyms
JI6;JAK3 INHIBITOR VI
CBNumber
CB3787012
Molecular Formula
C19H17N3O4S
Formula Weight
383.42098
MOL File
856436-16-3.mol
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JAK3 INHIBITOR VI Property

storage temp. 
+2C to +8C
form 
Yellow solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
420126
Product name
JAK3 Inhibitor VI - CAS 856436-16-3 - Calbiochem
Packaging
5MG
Price
$195
Updated
2023/06/20
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JAK3 INHIBITOR VI Chemical Properties,Usage,Production

General Description

A cell-permeable, potent, and reversible inhibitor of Janus kinase 3 (JAK3) (IC50 = 27 nM). Reported to bind to the enzyme active site and prevent IL-2-induced phosphorylation of JAK3 and STAT5. Also reported to inhibit IL-2-induced cell proliferation (IC50 = 760 nM for murine CTLL cells and 250 nM for human T-cells). Shown to alleviate oxazolone-induced ear edema in mice with an efficacy comparable to Dexamethasone (Cat. No. 265005) and displays ~16-fold greater selectivity over JAK2.

Biochem/physiol Actions

Cell permeable: yes

JAK3 INHIBITOR VI Preparation Products And Raw materials

Raw materials

Preparation Products

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JAK3 INHIBITOR VI Suppliers

China 8 United States 3 Global 11
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
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United States
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32161
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Creative Enzymes
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Email
info@creative-enzymes.com
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United States
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6057
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EMD Biosciences, Inc.
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Email
technical@calbiochem.com
Country
United States
ProdList
6529
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66

856436-16-3, JAK3 INHIBITOR VIRelated Search:


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