[2H5]-Quinapril

Product Name: [2H5]-Quinapril
CAS No.: 1279029-79-6
Chemical Name: [2H5]-Quinapril
Synonyms: [2H5]-Quinapril;2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenyl-d5-propyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid;Quinapril D5Q: What is Quinapril D5 Q: What is the CAS Number of Quinapril D5 Q: What is the storage condition of Quinapril D5 Q: What are the applications of Quinapril D5
CBNumber: CB38011283
Molecular Formula: C25H30N2O5
Formula Weight: 438.52
MOL File: 1279029-79-6.mol

More

Less

[2H5]-Quinapril Property

storage temp.: -20°C
solubility: Methanol: soluble
form: A solid

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

More

Less

[2H5]-Quinapril Chemical Properties,Usage,Production

Biological Activity

Quinapril-d5 is intended for use as an internal standard for the quantification of quinapril by GC- or LC-MS. Quinapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor quinaprilat.1,2 In vivo, quinapril (3 mg/kg) reduces mean arterial pressure in renal hypertensive and spontaneously hypertensive rats.2 It inhibits angiotensin I-induced pressor responses in normotensive rats and dogs. Quinapril (10-200 mg/kg) prevents left ventricular heart failure in CHF 14.6 cardiomyopathic hamsters. Formulations containing quinapril have been used in the treatment of hypertension, heart failure, and diabetic nephropathy.

References

1.Vago, T., Bevilacqua, M., Conci, F., et al.Angiotensin converting enzyme binding sites in human heart and lung: Comparison with rat tissuesBr. J. Pharmacol.107(3)821-825(1992) 2.Kaplan, H.R., Taylor, D.G., and Olson, S.C.Quinapril: Overview of preclinical dataClin. Cardiol.13(6 Suppl. 7)VII6-VII12(1990)

[2H5]-Quinapril Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

[2H5]-Quinapril Suppliers

China 8 India 1 United States 1 Global 10

ChemeGen 中国

Tel: 18818260767
Fax: QQ 3610331285
Email: 2625930290@qq.com
Country: China
ProdList: 6973
Advantage: 58

Beijing Biocreative Technology Co., Ltd.

Tel: 15522676233
Email: 3007606172@qq.com
Country: China
ProdList: 1248
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

Shanghai isotope chemical co.,ltd

Tel: 021-021-51600108 13062666369
Email: sales@chinaisotope.com
Country: China
ProdList: 4271
Advantage: 58

Nanjing Tengyi Biotechnology Co., Ltd

Tel: 025-58851786 17714337195
Email: sales@tybiochem.com
Country: China
ProdList: 6829
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11974
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 17301488900
Fax: 025-85560043
Email: judy.xia@synzest.com
Country: China
ProdList: 12582
Advantage: 58

1279029-79-6, [2H5]-QuinaprilRelated Search:

IBBLRJGOOANPTQ-GOMJJGCLSA-N Quinaprilat-D5 QUINAPRILAT HYDRATE

[2H5]-Quinapril

Quinapril D5Q: What is Quinapril D5 Q: What is the CAS Number of Quinapril D5 Q: What is the storage condition of Quinapril D5 Q: What are the applications of Quinapril D5

2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenyl-d5-propyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid

1279029-79-6