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AM-Imidazole-PA-Boc

Product Name
AM-Imidazole-PA-Boc
CAS No.
2357108-99-5
Chemical Name
AM-Imidazole-PA-Boc
Synonyms
AM-Imidazole-PA-Boc;tert-butyl (3-(4-(aminomethyl)-1H-imidazol-1-yl)propyl)carbamate;Carbamic acid, N-[3-[4-(aminomethyl)-1H-imidazol-1-yl]propyl]-, 1,1-dimethylethyl ester
CBNumber
CB38054655
Molecular Formula
C12H22N4O2
Formula Weight
254.33
MOL File
2357108-99-5.mol
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AM-Imidazole-PA-Boc Property

Boiling point:
463.0±30.0 °C(Predicted)
Density 
1.15±0.1 g/cm3(Predicted)
form 
Oil
pka
12.75±0.46(Predicted)
color 
Off-white to gray
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Hazard and Precautionary Statements (GHS)

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AM-Imidazole-PA-Boc Chemical Properties,Usage,Production

Biological Activity

AM-Imidazole-PA-Boc is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTAC IRAK4 degrader-1 [1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.

AM-Imidazole-PA-Boc Preparation Products And Raw materials

Raw materials

Preparation Products

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AM-Imidazole-PA-Boc Suppliers

TargetMol Chemicals Inc.
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United States
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TargetMol Chemicals Inc.
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Email
support@targetmol.com
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2357108-99-5, AM-Imidazole-PA-BocRelated Search:


  • AM-Imidazole-PA-Boc
  • Carbamic acid, N-[3-[4-(aminomethyl)-1H-imidazol-1-yl]propyl]-, 1,1-dimethylethyl ester
  • tert-butyl (3-(4-(aminomethyl)-1H-imidazol-1-yl)propyl)carbamate
  • 2357108-99-5