Aminooxy-amido-PEG4-propargyl
- Product Name
- Aminooxy-amido-PEG4-propargyl
- CAS No.
- 2253965-03-4
- Chemical Name
- Aminooxy-amido-PEG4-propargyl
- Synonyms
- Aminooxy-amido-PEG4-propargyl;Acetamide, 2-(aminooxy)-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl-
- CBNumber
- CB38054660
- Molecular Formula
- C13H24N2O6
- Formula Weight
- 304.34
- MOL File
- 2253965-03-4.mol
Aminooxy-amido-PEG4-propargyl Property
- Boiling point:
- 500.7±50.0 °C(Predicted)
- Density
- 1.134±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, sealed storage, away from moisture
- form
- Viscous Liquid
- pka
- 14.92±0.46(Predicted)
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
Aminooxy-amido-PEG4-propargyl Chemical Properties,Usage,Production
Uses
Aminooxy-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
Non-cleavable Linker
References
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
Aminooxy-amido-PEG4-propargyl Preparation Products And Raw materials
Raw materials
Preparation Products
Aminooxy-amido-PEG4-propargyl Suppliers
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- 400-400-164-7117 18317119277
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- China
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View Lastest Price from Aminooxy-amido-PEG4-propargyl manufacturers
- Product
- Aminooxy-amido-PEG4-propargyl 2253965-03-4
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-22