Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)-

Product Name: Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)-
CAS No.: 1904651-39-3
Chemical Name: Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)-
Synonyms: 7-(Difluoromethyl)-6-(1-methylpyrazol-4-yl)-1,2,3,4-tetrahydroquinoline;7-(Difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1,2,3,4-tetrahydroquinoline;7-(dif luoromethyl)-6-(1 -methyl-1 H-pyrazol-4-y1)-1,2,3,4-tetrahydroquinoline;Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)-
CBNumber: CB38085848
Molecular Formula: C14H15F2N3
Formula Weight: 263.29
MOL File: 1904651-39-3.mol

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Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)- Property

Boiling point:: 440.6±45.0 °C(Predicted)
Density: 1.33±0.1 g/cm3(Predicted)
solubility: Dichloromethane; Ethyl Acetate; Methanol
pka: 3.96±0.20(Predicted)
form: Solid
color: Off-White

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Hazard and Precautionary Statements (GHS)

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Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)- Chemical Properties,Usage,Production

Uses

7-(Difluoromethyl)-6-(1-methylpyrazol-4-yl)-1,2,3,4-tetrahydroquinoline is an intermediate in the synthesis of GNE-781 (D447825), a derivative of a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP). Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology.

Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)- Preparation Products And Raw materials

Raw materials

Preparation Products

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Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)- Suppliers

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1904651-39-3, Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)-Related Search:

Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)-

7-(Difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1,2,3,4-tetrahydroquinoline

7-(Difluoromethyl)-6-(1-methylpyrazol-4-yl)-1,2,3,4-tetrahydroquinoline

7-(dif luoromethyl)-6-(1 -methyl-1 H-pyrazol-4-y1)-1,2,3,4-tetrahydroquinoline

1904651-39-3