3-METHYLQUINOLIN-2-ONE
- Product Name
- 3-METHYLQUINOLIN-2-ONE
- CAS No.
- 2721-59-7
- Chemical Name
- 3-METHYLQUINOLIN-2-ONE
- Synonyms
- 3-methylcarbostyril;3-Methyl-2-quinolinone;3-METHYLQUINOLIN-2-ONE;3-methyl-3H-quinolin-2-one;3-Methylquinolin-2(1H)-one;3-methyl-1H-quinolin-2-one;3-Methyl-2(1H)-quinolinone;2(1H)-Quinolinone, 3-methyl-;3-methyl-1,2-dihydroquinolin-2-one;3-Methyl-1,2-dihydroquinoline-2-one
- CBNumber
- CB3836675
- Molecular Formula
- C10H9NO
- Formula Weight
- 159.18
- MOL File
- 2721-59-7.mol
3-METHYLQUINOLIN-2-ONE Property
- Melting point:
- 234-235 °C
- Boiling point:
- 346.0±35.0 °C(Predicted)
- Density
- 1.136±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 11.84±0.70(Predicted)
- LogP
- 1.850 (est)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M337458
- Product name
- 3-methyl-1,2-dihydroquinolin-2-one
- Packaging
- 10mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- CHM0010788
- Product name
- 3-METHYLQUINOLIN-2-ONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.79
- Updated
- 2021/12/16
- Product number
- 128522
- Product name
- 3-Methylquinolin-2-one
- Purity
- 97%
- Packaging
- 1g
- Price
- $791
- Updated
- 2021/12/16
- Product number
- 2544AB
- Product name
- 3-Methylquinolin-2(1H)-one
- Packaging
- 1g
- Price
- $1117
- Updated
- 2021/12/16
- Product number
- 2721597
- Product name
- 2-Hydroxy-3-methylquinoline
- Packaging
- 5g
- Price
- $1198.33
- Updated
- 2021/12/16
3-METHYLQUINOLIN-2-ONE Chemical Properties,Usage,Production
Uses
3-Methylcarbostyril (compound 5) is a BRD4 BD1 inhibitor with a pIC50 of 4.4[1].
Definition
ChEBI: 3-Methyl-quinolin-2-ol is a quinolone.
Synthesis Reference(s)
The Journal of Organic Chemistry, 38, p. 3740, 1973 DOI: 10.1021/jo00961a019
IC 50
BRD4 BD1: 4.4 (pIC50)
References
[1] Emmanuel H Demont, et al. Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors. J Med Chem. 2015 Jul 23;58(14):5649-73. DOI:10.1021/acs.jmedchem.5b00772
3-METHYLQUINOLIN-2-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
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