ChemicalBook > CAS DataBase List > 1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE

1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE

Product Name
1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE
CAS No.
180046-99-5
Chemical Name
1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE
Synonyms
SDZ NKT 343;1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE;L-Alaninamide, 1-[[(2-nitrophenyl)amino]carbonyl]-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)-
CBNumber
CB3839272
Molecular Formula
C33H33N5O5
Formula Weight
579.65
MOL File
180046-99-5.mol
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1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE Property

Boiling point:
892.8±65.0 °C(Predicted)
Density 
1.327±0.06 g/cm3(Predicted)
storage temp. 
Store at +4°C
solubility 
Soluble to 100 mM in DMSO and to 100 mM in ethanol
form 
Powder
pka
11.66±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
2394
Product name
SDZNKT343
Purity
≥98%(HPLC)
Packaging
10
Price
$241
Updated
2021/12/16
Usbiological
Product number
256646
Product name
SDZ NKT 343
Packaging
10mg
Price
$588
Updated
2021/12/16
TRC
Product number
S211123
Product name
SDZNKT343
Packaging
10mg
Price
$175
Updated
2021/12/16
TRC
Product number
S211123
Product name
SDZNKT343
Packaging
50mg
Price
$795
Updated
2021/12/16
TRC
Product number
S211123
Product name
SDZNKT343
Packaging
100mg
Price
$1400
Updated
2021/12/16
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1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE Chemical Properties,Usage,Production

Uses

SDZ NKT 343 is a potent human NK1 tachykinin receptor antagonist.

Biological Activity

Highly selective human tachykinin NK 1 receptor antagonist (IC 50 values are 0.62 and 451 nM for human and rat receptors respectively) that displays > 130-fold selectivity over human NK 2 and NK 3 receptors. Potently antagonizes SP-induced Ca 2+ efflux in vitro and inhibits mechanical hyperalgesia in vivo .

storage

Store at +4°C

1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE Suppliers

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180046-99-5, 1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDERelated Search:


  • 1-[[(2-NITROPHENYL)AMINO]CARBONYL]-L-PROLYL-N-METHYL-3-(2-NAPHTHALENYL)-N-(PHENYLMETHYL)-L-ALANINAMIDE
  • SDZ NKT 343
  • L-Alaninamide, 1-[[(2-nitrophenyl)amino]carbonyl]-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)-
  • 180046-99-5
  • C33H33N5O5
  • Highly selective human tachykinin NK1 receptor antagonist .