3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE
- Product Name
- 3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE
- CAS No.
- 21410-06-0
- Chemical Name
- 3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE
- Synonyms
- 3-benzyl-7-chlorotriazolo[4,5-d]pyrimidine;3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE;3-benzyl-7-chloro-3h - [1,2,3] thiazol [4,5-d] pyrimidine;3H-1,2,3-Triazolo[4,5-d]pyrimidine, 7-chloro-3-(phenylmethyl)-
- CBNumber
- CB3839474
- Molecular Formula
- C11H8ClN5
- Formula Weight
- 245.67
- MOL File
- 21410-06-0.mol
3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE Property
- Boiling point:
- 454.9±35.0 °C(Predicted)
- Density
- 1.50±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 0.98±0.30(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- FB139427
- Product name
- 3-Benzyl-7-chloro-3H-[1,2,3]-triazolo[4,5-d]pyrimidine
- Packaging
- 250mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- FB139427
- Product name
- 3-Benzyl-7-chloro-3H-[1,2,3]-triazolo[4,5-d]pyrimidine
- Packaging
- 500mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- W4446
- Product name
- 3-Benzyl-7-chloro-3H-[1,2,3]-triazolo[4,5-d]pyrimidine
- Packaging
- 500mg
- Price
- $320
- Updated
- 2021/12/16
- Product number
- FB139427
- Product name
- 3-Benzyl-7-chloro-3H-[1,2,3]-triazolo[4,5-d]pyrimidine
- Packaging
- 1g
- Price
- $380
- Updated
- 2021/12/16
- Product number
- 072379
- Product name
- 3-Benzyl-7-chloro-3H-[1,2,3]-triazolo[4,5-d]pyrimidine
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $416
- Updated
- 2021/12/16
3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE Chemical Properties,Usage,Production
Synthesis
21324-31-2
21410-06-0
General procedure for the synthesis of 3-benzyl-7-chloro-3H-[1,2,3]-triazolo[4,5-d]pyrimidines from 3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol: To chloroform (50 mL) containing 3-benzyl-7-hydroxy-3H-[1,2,3]triazolo[4,5-d]pyrimidines (10.56 mmol) suspension, N,N-dimethylformamide (DMF, 2 mL) and thionyl chloride (9 mL) were added sequentially. The reaction mixture was heated to reflux for 3 hours. After completion of the reaction, the solvent was removed by evaporation under reduced pressure at a temperature below 35 °C. The crude product was purified by silica gel column chromatography with mixed petroleum ether-ethyl acetate solvent as eluent. The final white solid product 3-benzyl-7-chloro-3H-[1,2,3]-triazolo[4,5-d]pyrimidine (1.14 g, 44% yield) was obtained.
References
[1] Patent: EP1598354, 2005, A1. Location in patent: Page/Page column 88
3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
3-BENZYL-7-CHLORO-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE Suppliers
- Tel
- 001-857-928-2050 or 1-888-588-9418
- Fax
- 001-617-206-9595
- sales@chemreagents.com
- Country
- United States
- ProdList
- 10186
- Advantage
- 62
- Tel
- 8485655694
- sales@alchempharmtech.com
- Country
- United States
- ProdList
- 63687
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@combi-blocks.com
- Country
- United States
- ProdList
- 6618
- Advantage
- 69
- Tel
- --
- Fax
- --
- sales@matrixscientific.com
- Country
- United States
- ProdList
- 6632
- Advantage
- 80