ChemicalBook > CAS DataBase List > 2-(4-CHLORO-PHENYLETHYNYL)-PHENYLAMINE

2-(4-CHLORO-PHENYLETHYNYL)-PHENYLAMINE

Product Name
2-(4-CHLORO-PHENYLETHYNYL)-PHENYLAMINE
CAS No.
221910-19-6
Chemical Name
2-(4-CHLORO-PHENYLETHYNYL)-PHENYLAMINE
Synonyms
2-((4-Chlorophenyl)ethynyl)aniline;2-(4-CHLORO-PHENYLETHYNYL)-PHENYLAMINE;2-[2-(4-Chlorophenyl)ethynyl]benzenamine;Benzenamine, 2-[2-(4-chlorophenyl)ethynyl]-;2-((4-Chlorophenyl)ethynyl)aniline - [C57481]
CBNumber
CB3840636
Molecular Formula
C14H10ClN
Formula Weight
227.69
MOL File
Mol file
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2-(4-CHLORO-PHENYLETHYNYL)-PHENYLAMINE Property

storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Synthonix
Product number
C57481
Product name
2-((4-Chlorophenyl)ethynyl)aniline
Purity
97%
Packaging
100mg
Price
$20
Updated
2021/12/16
Synthonix
Product number
C57481
Product name
2-((4-Chlorophenyl)ethynyl)aniline
Purity
97%
Packaging
250mg
Price
$40
Updated
2021/12/16
Synthonix
Product number
C57481
Product name
2-((4-Chlorophenyl)ethynyl)aniline
Purity
97%
Packaging
1g
Price
$110
Updated
2021/12/16
Activate Scientific
Product number
AS47627
Product name
2-((4-Chlorophenyl)ethynyl)aniline
Purity
97%
Packaging
1g
Price
$162
Updated
2021/12/16
Synthonix
Product number
C57481
Product name
2-((4-Chlorophenyl)ethynyl)aniline
Purity
97%
Packaging
5g
Price
$430
Updated
2021/12/16
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2-(4-CHLORO-PHENYLETHYNYL)-PHENYLAMINE Chemical Properties,Usage,Production

Synthesis

873-73-4

615-43-0

221910-19-6

PdCl2(PPh3)2 (88 mg, 0.125 mmol), CuI (24 mg, 0.125 mmol) and THF (5 mL) were added to an oven-dried, two-necked round-bottomed flask under standard reaction conditions. To this suspension, 2-iodoaniline (5.47 mg, 2.5 mmol) and triethylamine (702 μL, 5.0 mmol) were sequentially added. The reaction mixture was degassed by argon bubbling for 15 min. Subsequently, 4-chlorophenylacetylene (300 μL, 2.75 mmol) was added and the reaction mixture was stirred at room temperature. The progress of the reaction was monitored by thin-layer chromatography (TLC), and after complete consumption of 2-iodoaniline (about 2 h), the reaction mixture was filtered through diatomaceous earth and the solvent was removed by rotary evaporation to obtain the crude product. The crude product was further purified by column chromatography on silica gel (60-120 mesh) using ethyl acetate/hexane (1:9, v/v) as eluent, resulting in purified 2-((4-chlorophenyl)alkynyl)-aniline (400 mg, 83% yield).

References

[1] Dalton Transactions, 2017, vol. 46, # 5, p. 1539 - 1545
[2] Tetrahedron Letters, 2014, vol. 55, # 40, p. 5495 - 5498
[3] Tetrahedron, 2011, vol. 67, # 46, p. 8918 - 8924
[4] Journal of Organic Chemistry, 2012, vol. 77, # 1, p. 617 - 625
[5] Journal of Organic Chemistry, 2013, vol. 78, # 20, p. 10319 - 10328

2-(4-CHLORO-PHENYLETHYNYL)-PHENYLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(4-CHLORO-PHENYLETHYNYL)-PHENYLAMINE Suppliers

China 6 India 1 United Kingdom 1 United States 5 Global 13
A.J Chemicals
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221910-19-6, 2-(4-CHLORO-PHENYLETHYNYL)-PHENYLAMINERelated Search:


  • 2-(4-CHLORO-PHENYLETHYNYL)-PHENYLAMINE
  • 2-((4-Chlorophenyl)ethynyl)aniline
  • Benzenamine, 2-[2-(4-chlorophenyl)ethynyl]-
  • 2-[2-(4-Chlorophenyl)ethynyl]benzenamine
  • 2-((4-Chlorophenyl)ethynyl)aniline - [C57481]
  • 221910-19-6