ChemicalBook > CAS DataBase List > 4-(5-HYDROXYMETHYLIMIDAZOL-1-YLMETHYL)BENZONITRILE
4-(5-HYDROXYMETHYLIMIDAZOL-1-YLMETHYL)BENZONITRILE
- Product Name
- 4-(5-HYDROXYMETHYLIMIDAZOL-1-YLMETHYL)BENZONITRILE
- CAS No.
- 183500-36-9
- Chemical Name
- 4-(5-HYDROXYMETHYLIMIDAZOL-1-YLMETHYL)BENZONITRILE
- Synonyms
- CYP19A1/CYP11B2-IN-1;4-(5-HYDROXYMETHYLIMIDAZOL-1-YLMETHYL)BENZONITRILE
- CBNumber
- CB3846764
- Molecular Formula
- C12H11N3O
- Formula Weight
- 213.23524
- MOL File
- 183500-36-9.mol
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4-(5-HYDROXYMETHYLIMIDAZOL-1-YLMETHYL)BENZONITRILE Property
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- CHM0372672
- Product name
- 4-(5-HYDROXYMETHYLIMIDAZOL-1-YLMETHYL)BENZONITRILE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.14
- Updated
- 2021/12/16
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4-(5-HYDROXYMETHYLIMIDAZOL-1-YLMETHYL)BENZONITRILE Chemical Properties,Usage,Production
Uses
CYP19A1/CYP11B2-IN-1 (Compound X21) is a potent and selective aromatase and aldosterone synthase dual inhibitor with IC50s of 2.3 nM and 29 nM for aromatase (CYP19A1) and aldosterone synthase (CYP11B2), respectively. CYP19A1/CYP11B2-IN-1 has excellent antiproliferative and pro-apoptotic activity against the cancer cell. CYP19A1/CYP11B2-IN-1 can be used for research of breast cancer[1].
References
[1] Tinivella A, et al. Discovery of a Potent Dual Inhibitor of Aromatase and Aldosterone Synthase. ACS Pharmacology & Translational Science. 2023 Nov 23. DOI:10.1021/acsptsci.3c00183
4-(5-HYDROXYMETHYLIMIDAZOL-1-YLMETHYL)BENZONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
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4-(5-HYDROXYMETHYLIMIDAZOL-1-YLMETHYL)BENZONITRILE Suppliers
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- Country
- United States
- ProdList
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