3-Methylseleno-L-alanine Hydrochloride
- Product Name
- 3-Methylseleno-L-alanine Hydrochloride
- CAS No.
- 863394-07-4
- Chemical Name
- 3-Methylseleno-L-alanine Hydrochloride
- Synonyms
- 3-(Methylseleno)-Ala-OH.HCl;Se-Methylselenocysteine HCL;3-Methylseleno-L-alanine Hydrochloride;Se-
(Methyl) selenocysteine hydrochloride;Se-(Methyl)selenocysteine hydrochloride >=95% (TLC);(R)-2-aMino-3-(Methylselanyl)propanoic acid hydrochloride - CBNumber
- CB3854480
- Molecular Formula
- C4H10ClNO2Se
- Formula Weight
- 218.5407
- MOL File
- 863394-07-4.mol
3-Methylseleno-L-alanine Hydrochloride Property
- storage temp.
- -20°C
- solubility
- DMF: 1 mg/ml,DMSO: 1 mg/ml,PBS (pH 7.2): 10 mg/ml
- form
- A crystalline solid
Safety
- Hazard Codes
- T,N
- Risk Statements
- 23/25-33-50/53
- Safety Statements
- 20/21-28-45-60-61
- RIDADR
- UN 3283 6.1/PG 2
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H373May cause damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P273Avoid release to the environment.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P314Get medical advice/attention if you feel unwell.
N-Bromosuccinimide Price
- Product number
- M6680
- Product name
- Se-(Methyl)selenocysteine hydrochloride
- Purity
- ≥95% (TLC)
- Packaging
- 100mg
- Price
- $304.95
- Updated
- 2025/07/31
- Product number
- AAA0003372
- Product name
- SE-(METHYL)SELENOCYSTEINE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $745.24
- Updated
- 2021/12/16
- Product number
- 350105
- Product name
- 3-(Methylseleno)-L-alanine•HCl
- Packaging
- 1g
- Price
- $1076
- Updated
- 2021/12/16
- Product number
- 350105
- Product name
- 3-(Methylseleno)-L-alanine•HCl
- Packaging
- 5g
- Price
- $2959
- Updated
- 2021/12/16
- Product number
- CD21001893
- Product name
- 3-(Methylseleno)-Ala-OH.HCl
- Purity
- 97%
- Packaging
- 1g
- Price
- $1320
- Updated
- 2021/12/16
3-Methylseleno-L-alanine Hydrochloride Chemical Properties,Usage,Production
Uses
Se-(Methyl) selenocysteine hydrochloride has been used as a standard in fluorescence-XANES (X-ray absorption near-edge spectroscopy) imaging.
General Description
Selenium (Se)-(Methyl) selenocysteine (MeSeCys) is a methylated product of selenocysteine, this reaction is catalyzed by selenocysteine methyltransferase (SMT) in Astragalus bisulcatus.
Biochem/physiol Actions
Selenium (Se)-(Methyl) selenocysteine functions as a potent chemotherapeutic agent for human breast cancer. Enhanced production of methlylselenol from L-Se-methylselenocysteine in vivo alters redox status of cells and oxidatively triggers cellular apoptosis. It is implicated in inhibition of mammary tumor formation in rats.
in vivo
Se-Methylselenocysteine hydrochloride (0.2?mg/mouse; p.o.; daily for 14 days) potentiates the antitumour activity of CDDP and Cyclophosphamide in nude mice bearing human FaDu and A253 head and neck xenografts[2].
?
Alzheimer's disease (AD) mice are treats with Se-Methylselenocysteine hydrochloride (0.75 mg/kg BW per day) in their drinking water for 10 months. Se-Methylselenocysteine hydrochloride reduces oxidative stress and neuro-inflammation; Se-Methylselenocysteine hydrochloride modulates the distribution and levels of several metal ions; Se-Methylselenocysteine hydrochloride decreases amyloid-β peptide (Aβ) generation by inhibiting the expression of its precursor protein APP and β-secretase (BACE1), and attenuates tau hyperphosphorylation and neurofibrillary tangles (NFT) formation via promoting protein phosphatase 2A (PP2A) activity, thereby preserving synaptic proteins and neuron activities and finally improving spatial learning and memory deficits in AD model mice[3].
3-Methylseleno-L-alanine Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
3-Methylseleno-L-alanine Hydrochloride Suppliers
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 512-58900862 400-0707518
- Fax
- 0086-512-56765862
- sales@alabiochem.com
- Country
- China
- ProdList
- 970
- Advantage
- 59
- Tel
- 010-62651721 18610486005
- Fax
- 01062651521-808
- minghui.yu@okeanos.com.cn
- Country
- China
- ProdList
- 495
- Advantage
- 60
- Tel
- 020-39119399 18927568969
- Fax
- 020-39119999
- isunpharm@qq.com
- Country
- China
- ProdList
- 4720
- Advantage
- 55
- Tel
- 15221275939
- Fax
- 021-50706099
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 15873
- Advantage
- 55
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51395
- Advantage
- 80
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9803
- Advantage
- 58
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 025-52078417 17701591256
- sales@fine-chemtech.com
- Country
- China
- ProdList
- 288
- Advantage
- 58
- Tel
- 010-60605840 18892239720
- Fax
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 12306
- Advantage
- 58
- Tel
- 025-66113011 13155353615
- Fax
- (7)02557626880
- qzhang@aikonchem.com
- Country
- China
- ProdList
- 15394
- Advantage
- 58
- Tel
- 0411-39042497
- Fax
- 0411-39042693
- sales@alphabiopharm.com
- Country
- China
- ProdList
- 1951
- Advantage
- 58
- Tel
- +86-0571-81612335 +8613336028439
- sales@nextpeptide.com
- Country
- China
- ProdList
- 19908
- Advantage
- 58
- Tel
- 18221292452
- fannieliu@glschina.com
- Country
- China
- ProdList
- 6798
- Advantage
- 58
- Tel
- 18818260767
- Fax
- QQ 3610331285
- sales@chemegen.com
- Country
- China
- ProdList
- 11218
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing@energy-chemical.com
- Country
- China
- ProdList
- 44918
- Advantage
- 58
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29757
- Advantage
- 58
- Tel
- 400-1647117 13681763483
- product02@bidepharm.com
- Country
- China
- ProdList
- 59936
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24961
- Advantage
- 58
- Tel
- 0571-8512-5372
- sales@bingochem.com
- Country
- China
- ProdList
- 21669
- Advantage
- 58
- Tel
- 15223382610
- danny@chemdad.com
- Country
- China
- ProdList
- 2032
- Advantage
- 58
- Tel
- 4008-099-669
- 23419001name@qq.com
- Country
- CHINA
- ProdList
- 6043
- Advantage
- 58
- Tel
- 18201332838
- 3032079623@qq.com
- Country
- China
- ProdList
- 6695
- Advantage
- 58
- Tel
- 800-364-9897
- sales@caymanchem.com
- Country
- China
- ProdList
- 6838
- Advantage
- 58
- Tel
- 21-20338288
- ordercn@merckgroup.com
- Country
- China
- ProdList
- 6394
- Advantage
- 58
- Tel
- +86-0755-89396905 +86-18025329037
- admin@nexconn.com
- Country
- China
- ProdList
- 3255
- Advantage
- 58
- Tel
- +undefined86-15223382610
- info@jooe.com
- Country
- China
- ProdList
- 6208
- Advantage
- 58
- Tel
- +86-571-87711850
- market18@leapchem.com
- Country
- China
- ProdList
- 24727
- Advantage
- 58
- Tel
- 13826205800
- Country
- CHINA
- ProdList
- 154
- Advantage
- 58