paraflutizide

Product Name: paraflutizide
CAS No.: 1580-83-2
Chemical Name: paraflutizide
Synonyms: LD-3612;Paraflutizida;paraflutizide;6-Chloro-3-(p-fluorobenzyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide;6-chloro-3-(4-fluorobenzyl)-1,1-diketo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide;6-chloro-3-[(4-fluorophenyl)methyl]-1,1-dioxo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide;2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-[(4-fluorophenyl)methyl]-3,4-dihydro-, 1,1-dioxide
CBNumber: CB3875049
Molecular Formula: C14H13ClFN3O4S2
Formula Weight: 405.85
MOL File: 1580-83-2.mol

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paraflutizide Property

Melting point:: 238-240°
Boiling point:: 636.2±65.0 °C(Predicted)
Density: 1.571±0.06 g/cm3(Predicted)
pka: 8.66±0.40(Predicted)

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Safety

Toxicity: LD50 oral in mouse: > 10gm/kg

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0012179
Product name: PARAFLUTIZIDE
Purity: 95.00%
Packaging: 5MG
Price: $502.47
Updated: 2021/12/16

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paraflutizide Chemical Properties,Usage,Production

Originator

Paraflutizide, Shanghai Lansheng

Manufacturing Process

A mixture of 5.0 g (0.0357 g/mol) of ρ-fluorophenylethyl alcohol, 2.0 g (0.007 g/mol) of 5-chloro-2,4-disulphamylaniline, 2.0 g (0.0068 g/mol) of potassium bichromate and 15 ml of concentrated hydrochloric acid (0.176 g/mol) and 25 ml of water is heated under reflux for 1 h. The mixture is allowed to cool, and 15 ml of ether are added to separate the excess of ρ-fluorophenylethyl alcohol. The aqueous layer is decanted and frozen for 2 h and the precipitate is separated, washed with water and dried in vacuum over phosphoric anhydride. There are collected 1.35 g (yield 47.5%) of the 1,1-dioxide of 3-ρfluorophenyl-methyl-7-sulphamyl-6-chloro-3,4-dihydrobenzo-1,2,4-thiadiazine, which when recrystallised from 30 ml of 50% alcohol on "Norit" active carbon takes the form of a white crystalline substance, melting point is 239°C.

Therapeutic Function

Diuretic

paraflutizide Preparation Products And Raw materials

Raw materials

Preparation Products

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paraflutizide Suppliers

China 5 South Korea 1 United States 3 Global 9

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32063
Advantage: 58

Shaanxi DIDU pharmaceutical and Chemical Co., Ltd

Tel: 15229059051
Email: 1027@dideu.com
Country: China
ProdList: 9982
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24648
Advantage: 58

TargetMol Chemicals Inc.

Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Country: United States
ProdList: 19863
Advantage: 58

Hangzhou MolCore BioPharmatech Co.,Ltd.

Tel: +86-057181025280; +8617767106207
Fax: 0571-85806285
Email: sales@molcore.com
Country: China
ProdList: 49734
Advantage: 58

1580-83-2, paraflutizideRelated Search:

Chlorothiazide Hydrochlorothiazide BENZYLHYDROCHLOROTHIAZIDE paraflutizide 4-Amino-6-chlorobenzene-1,3-disulfonamide 2-amino-N-propylbenzenesulfonamide ethiazide

paraflutizide

6-Chloro-3-(p-fluorobenzyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

LD-3612

6-chloro-3-(4-fluorobenzyl)-1,1-diketo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide

6-chloro-3-[(4-fluorophenyl)methyl]-1,1-dioxo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide

2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-[(4-fluorophenyl)methyl]-3,4-dihydro-, 1,1-dioxide

Paraflutizida

1580-83-2

C14H13ClFN3O4S2