cloral betaine Property

Melting point:

122.5-124.5°

Safety

Toxicity

LD50 oral in mouse: 800mg/kg

DEA Controlled Substances

CSCN: 2460
CSA SCH: Schedule IV
NARC: No

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

cloral betaine Chemical Properties,Usage,Production

Originator

Beta-Chlor,Mead Johnson,US,1963

Uses

Sedative-hypnotic.

Manufacturing Process

An intimate mixture of betaine hydrate (67.5 g) and chloral hydrate (100 g) was warmed to ca. 60°C when an exothermic reaction occurred and the mixture became pasty. It was then stirred at 60°C for 30 minutes. The residue solidified on cooling and was crystallized from a small amount of water. The product separated in hard, colorless prisms of MP 122.5 to 124.5°C (corr).

Therapeutic Function

Sedative