rifamide

Product Name: rifamide
CAS No.: 2750-76-7
Chemical Name: rifamide
Synonyms: M/14;rifamide;Rifomide;Rifamycin M-14;Rifomycin M-14;rifamide USP/EP/BP;Rifamycin B diethylamide;Rifomycin B diethylamide;Rifamycin, 4-O-[2-(diethylamino)-2-oxoethyl]-
CBNumber: CB3908402
Molecular Formula: C43H58N2O13
Formula Weight: 810.93
MOL File: 2750-76-7.mol

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rifamide Property

Melting point:: 170°C (rough estimate)
Boiling point:: 755.63°C (rough estimate)
alpha: D20 -48.7° (c = 0.4 in methanol)
Density: 1.1791 (rough estimate)
refractive index: 1.4670 (estimate)

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Safety

Toxicity: LD50 in mice, rats (mg/kg): 2450, >4000 orally; 640, 2500 s.c.; 320, 535 i.p.; 315, 380 i.v. (Dezulian)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Adipogen Life Sciences

Product number: AG-CN2-0332-M010
Product name: RifamycinM14
Purity: ≥95%(HPLC)
Packaging: 10mg
Price: $90
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0012412
Product name: RIFAMIDE
Purity: 95.00%
Packaging: 5MG
Price: $502.55
Updated: 2021/12/16

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rifamide Chemical Properties,Usage,Production

Uses

Antibacterial.

Pharmaceutical Applications

The diethyl amide of rifamycin B, formulated as the sodium salt for parenteral administration. It exhibits high activity against Gram-positive organisms and M. tuberculosis typical of the group. MICs for Gram-negative bacilli are of the order of 20–50 mg/L.
It is absorbed orally and is rapidly eliminated through the bile, achieving concentrations sufficient to inhibit Gramnegative bacilli. In contrast to rifampicin, it can be administered as the sodium salt by intramuscular injection. A dose of 150 mg produces mean plasma levels of about 1 mg/L. The plasma halflife is about 2 h. The same dosage produces concentrations over 1 g/L in bile and c. 40 mg/L in the gallbladder wall.
Toxicity and side effects are similar to those of other rifamycins. It has been used in staphylococcal infections and infections of the biliary tract. It is unsuitable for the treatment of tuberculosis because of insufficient distribution to the tissues.

rifamide Preparation Products And Raw materials

Raw materials

Preparation Products

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rifamide Suppliers

China 23 United States 1 Global 24

Shanghai EFE Biological Technology Co., Ltd.

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2750-76-7, rifamideRelated Search:

rifamide

M/14

Rifamycin B diethylamide

Rifamycin M-14

Rifomide

Rifomycin B diethylamide

Rifomycin M-14

Rifamycin, 4-O-[2-(diethylamino)-2-oxoethyl]-

rifamide USP/EP/BP

2750-76-7

C43H58N2O13