sulforidazine
- Product Name
- sulforidazine
- CAS No.
- 14759-06-9
- Chemical Name
- sulforidazine
- Synonyms
- sulforidazine;Thioridazine 2-Sulfone;Thioridazine EP Impurity E;Thioridazine Impurity 5 (Thioridazine EP Impurity E);10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)-;10-[2-[(2RS)-1-Methylpiperidin-2-yl]ethyl]-2-(methylsulfonyl)-10H-phenothiazine;10-[2-[(2RS)-1-methylpiperidin-2-yl]ethyl]-2-(methylsulfonyl)-10H-phenothiazine (sulforidazine);10-(2-(1-Methylpiperidin-2-yl)ethyl)-2-(methylsulfonyl)-10H-phenothiazine (Thioridazine Impurity)
- CBNumber
- CB3920154
- Molecular Formula
- C21H26N2O2S2
- Formula Weight
- 402.57
- MOL File
- 14759-06-9.mol
sulforidazine Property
- Melting point:
- 121-123°
- Boiling point:
- 589.1±50.0 °C(Predicted)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator, Under Inert Atmosphere
- solubility
- Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 9.83±0.10(Predicted)
- color
- Off-White to Dark Yellow
N-Bromosuccinimide Price
- Product number
- T368810
- Product name
- Thioridazine2-Sulfone
- Packaging
- 50mg
- Price
- $1455
- Updated
- 2021/12/16
- Product number
- API0012528
- Product name
- SULFORIDAZINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $345.4
- Updated
- 2021/12/16
- Product number
- AA001EXB
- Product name
- 10H-Phenothiazine,10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)-
- Packaging
- 5mg
- Price
- $315
- Updated
- 2021/12/16
- Product number
- AA001EXB
- Product name
- 10H-Phenothiazine,10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)-
- Packaging
- 50mg
- Price
- $1470
- Updated
- 2021/12/16
sulforidazine Chemical Properties,Usage,Production
Chemical Properties
Thick Yellow Oil
Originator
Sulforidazine,ZYF Pharm Chemical
Uses
Thioridazine 2-Sulfone (Thioridazine EP Impurity E) is a major metabolite of Thioridazine (THD 2-SO2).
Definition
ChEBI: Sulforidazine is a member of phenothiazines.
Manufacturing Process
A mixture of 96.5 g 2-methylsulfonylphenothiazine, 50 g 2-(2-chloroethyl)-1- methylpiperidine, 62 g diethyl carbonate and 2 g sodium methylate was heated at 135°C for 1 hour and then at 180-190°C for 2.5 hours. The product was dissolved in benzene (500 ml) and the solution was extracted with 700 ml of 15% aqueous solution tartaric acid. The extract was washed with benzene. After addition of sodium carbonate solution to the extract was obtained a precipitate which was dissolved in benzene. This solution was washed with water and concentrated. 2-Methylsulfonyl-10-(2-(1-methyl-2- piperidyl)ethyl)phenothiazin was recrystallized from acetone, melting point 121-123°C.
Therapeutic Function
Neuroleptic
sulforidazine Preparation Products And Raw materials
Raw materials
Preparation Products
sulforidazine Suppliers
- Tel
- --
- Fax
- --
- info@trc-canada.com
- Country
- Canada
- ProdList
- 6088
- Advantage
- 71