O-(2,4-dinitrophenyl)hydroxylamine
- Product Name
- O-(2,4-dinitrophenyl)hydroxylamine
- CAS No.
- 17508-17-7
- Chemical Name
- O-(2,4-dinitrophenyl)hydroxylamine
- Synonyms
- 2,4-Dinitrophenylhydroxylamine;NSC 148499;2,4-NitrophenoxyaMine;2,4-DinitrophenoxyaMine;4-dinitrophenyl)hydroxylamine;1-aMinooxy-2,4-dinitro-benzene;O-(2,4-dinitrophenyl)hydroxylamine;HydroxylaMine,O-(2,4-dinitrophenyl)-;O-(2,4-Dinitrophenyl)hydroxylamine,98%;TIANFUCHEM--17508-17-7---O-(2,4-dinitrophenyl)hydroxylamine
- CBNumber
- CB3922714
- Molecular Formula
- C6H5N3O5
- Formula Weight
- 199.12
- MOL File
- 17508-17-7.mol
O-(2,4-dinitrophenyl)hydroxylamine Property
- Melting point:
- 112.5°C
- Boiling point:
- 336.62°C (rough estimate)
- Density
- 1.6937 (rough estimate)
- refractive index
- 1.6910 (estimate)
- storage temp.
- 2-8°C(protect from light)
- solubility
- DMSO (Sparingly), Methanol (Slightly)
- form
- solid
- pka
- -1.07±0.70(Predicted)
- color
- yellow
Safety
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26
- TSCA
- No
- HS Code
- 29221990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D5103
- Product name
- O-(2,4-Dinitrophenyl)hydroxylamine
- Packaging
- 1G
- Price
- $81
- Updated
- 2024/03/01
- Product number
- D5103
- Product name
- O-(2,4-Dinitrophenyl)hydroxylamine
- Packaging
- 5G
- Price
- $282
- Updated
- 2024/03/01
- Product number
- D479985
- Product name
- O-(2,4-Dinitrophenyl)hydroxylamine
- Packaging
- 5g
- Price
- $110
- Updated
- 2021/12/16
- Product number
- FD22435
- Product name
- O-(2,4-Dinitrophenyl)hydroxylamine
- Packaging
- 5G
- Price
- $150
- Updated
- 2021/12/16
- Product number
- FD22435
- Product name
- O-(2,4-Dinitrophenyl)hydroxylamine
- Packaging
- 10g
- Price
- $200
- Updated
- 2021/12/16
O-(2,4-dinitrophenyl)hydroxylamine Chemical Properties,Usage,Production
Chemical Properties
Light yellow solid
Uses
Efficient agent for metal-free amination of arylboronic acids leading to primary anilines. Reagents used in Rhodium-catalyzed aziridines formation.
Uses
O-(2,4-Dinitrophenyl)hydroxylamine is a rapid active-site-directed inhibitor of D-amino acid oxidase; modification results in specific incorporation of an amine group into an accessible nucleophilic r esidue with concomitant release of 2,4-dinitrophenol.
Preparation
To a stirred solution of 13.3 gm (0.1 mole) of t-butyl JV-hydroxycar-bamate and 5.6 gm (0.1 mole) of potassium hydroxide in 200 ml of absolute ethanol is added 20.2 gm (0.1 mole) of 2,4-dinitrochlorobenzene. The resultant deep red solution is stirred at room temperature for 1 hr; then enough glacial acetic acid is added dropwise to produce a light yellow solution. The solution is poured into 1.5 liters of cold water. The yellow oil which separates is gradually converted to crystals. The solid ?-butyl JV-(2,4-dinitrophenoxy)carbamate is separated, dried, and recrystallized from an ethyl acetate-hexane mixture to afford 16.4 gm (53%), m.p. 74-75°C. To 15 ml of trifluoroacetic acid is added 4 gm (0.0133 mole) of the i-butyl J/V-(2,4-dinitrophenoxy)carbamate. After the evolution of carbon dioxide has subsided, the solution is poured into 100 ml of ice water. The resultant oily layer crystallizes on standing to afford 2.5 gm (95%), m.p. 112°C (from ethanol).
Recently it was discovered that the alkylation of ethyl JV-hydroxy-carbamate under alkaline conditions, particularly in a DMF medium at 60°C in the presence of sodium bicarbonate, leads to the ultimate formation of O-alkylated hydroxylamines. On the other hand, at 80-85°C, the direct alkylation without the presence of a base ultimately leads to N-alkylhydrox-ylamines (see Table I) [59]. The reaction of ethylazidoformate with an alcohol, while perhaps hazardous, may have some merit (Eqs. 31-33). The overall yield, based on ethyl chloroformate, is said to be on the order of 60%.
O-(2,4-dinitrophenyl)hydroxylamine Preparation Products And Raw materials
Raw materials
Preparation Products
O-(2,4-dinitrophenyl)hydroxylamine Suppliers
View Lastest Price from O-(2,4-dinitrophenyl)hydroxylamine manufacturers
- Product
- O-(2,4-dinitrophenyl)hydroxylamine 17508-17-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- O-(2,4-dinitrophenyl)hydroxylamine 17508-17-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08
- Product
- O-(2,4-dinitrophenyl)hydroxylamine 17508-17-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2018-08-06