piperylone

Product Name: piperylone
CAS No.: 2531-04-6
Chemical Name: piperylone
Synonyms: PR66;piperylone;Piperylonum;4-ethyl-2-(1-methyl-4-piperidyl)-5-phenyl-1H-pyrazol-3-one;4-ethyl-2-(1-methylpiperidin-4-yl)-5-phenyl-1H-pyrazol-3-one;4-Ethyl-1,2-dihydro-2-(1-methylpiperidin-4-yl)-5-phenyl-3H-pyrazol-3-one;3H-Pyrazol-3-one, 4-ethyl-1,2-dihydro-2-(1-methyl-4-piperidinyl)-5-phenyl-
CBNumber: CB3941405
Molecular Formula: C17H23N3O
Formula Weight: 285.38
MOL File: 2531-04-6.mol

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piperylone Property

Boiling point:: 413.0±55.0 °C(Predicted)
Density: 1.121±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: pK1 5.90; pK2 9.15(at 25℃)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0025849
Product name: PIPERYLONE
Purity: 95.00%
Packaging: 5MG
Price: $498.96
Updated: 2021/12/16

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piperylone Chemical Properties,Usage,Production

Originator

Palerol, Novartis

Uses

Piperylone can be used as an antispasmodic.

Manufacturing Process

A mixture of 8.8 parts of α-ethylbenzoylacetic acid ethyl ester and 5,3 parts of N-methyl-piperidyl-4-hydrazine is allowed to stand for 30 min at 22°C, after which the mixture is heated for 5 hours to 130°C under a pressure of 12 mm. After 4 hours 1-(N-methylpiperidyl-4)-3-phenyl-4-ethylpyrazolone-5 begins crystallize out. The reaction mixture is allowed to cool, after which the crystal mass is triturated with ether and then recrystallized from methanol-ether or from acetone. Melting point 159-161°C.

Therapeutic Function

Analgesic

References

[1] Martínková J, et al. A study of the inhibition of adrenaline-induced vasoconstriction in the isolated perfused liver of rabbit. Hepatology. 1990 Nov;12(5):1157-65. DOI:10.1002/hep.1840120514

piperylone Preparation Products And Raw materials

Raw materials

Preparation Products

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piperylone Suppliers

China 7 Europe 2 United States 4 Global 13

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Shaanxi DIDU pharmaceutical and Chemical Co., Ltd

Tel: 029-029-029-81148696 18161915376
Email: 1040@dideu.com
Country: China
ProdList: 10001
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
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Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354;
Email: support@targetmol.com
Country: United States
ProdList: 39035
Advantage: 58

2531-04-6, piperyloneRelated Search:

Dimethylamino propyl methacrylamide N-(3-AMINOPROPYL) METHACRYLAMIDE piperylone N,N-Dimethylaminopropyl acrylamide 4-hydrazinyl-1-methylpiperidine benzpiperylone

piperylone

Piperylonum

4-Ethyl-1,2-dihydro-2-(1-methylpiperidin-4-yl)-5-phenyl-3H-pyrazol-3-one

4-ethyl-2-(1-methyl-4-piperidyl)-5-phenyl-1H-pyrazol-3-one

4-ethyl-2-(1-methylpiperidin-4-yl)-5-phenyl-1H-pyrazol-3-one

PR66

3H-Pyrazol-3-one, 4-ethyl-1,2-dihydro-2-(1-methyl-4-piperidinyl)-5-phenyl-

2531-04-6