[LEU27]-MELAN-A
- Product Name
- [LEU27]-MELAN-A
- CAS No.
- 204060-45-7
- Chemical Name
- [LEU27]-MELAN-A
- Synonyms
- ELAGIGILTV;MART 1 (26-35);Melan-A/MART-1;MART 1 (26-35);[LEU27]-MELAN-A;Melan-A/MART-1 analog;[Leu27]-Melan-A, MART 1 (26-35);H-GLU-LEU-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL-OH;Melan-A/MART-1 analog ([Leu27]-Melan-A, MART-1 (26-35));L-Valine, L-α-glutamyl-L-leucyl-L-alanylglycyl-L-isoleucylglycyl-L-isoleucyl-L-leucyl-L-threonyl-
- CBNumber
- CB3945968
- Molecular Formula
- C45H80N10O14
- Formula Weight
- 985.18
- MOL File
- 204060-45-7.mol
[LEU27]-MELAN-A Property
- Boiling point:
- 1353.421±65.00 °C(Press: 760.00 Torr)(predicted)
- Density
- 1.201±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
- pka
- 3.322±0.10(predicted)
- Sequence
- Glu-Leu-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val
[LEU27]-MELAN-A Chemical Properties,Usage,Production
Uses
Melan-A/MART-1 analog ([Leu27]-Melan-A, MART-1 (26-35)) is a biological active peptide. (This Melan-A (26-35) analog, Leu substituted for Ala at position 27, shows better HLA-A*0201 binding properties as well as better immunogenicity and antigenicity than the natural Melan-A (26-35).Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)
[LEU27]-MELAN-A Preparation Products And Raw materials
Raw materials
Preparation Products
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