Caffeine Citrate
- Product Name
- Caffeine Citrate
- CAS No.
- 93390-81-9
- Chemical Name
- Caffeine Citrate
- Synonyms
- XWLUWCNOOVRFPX-UHFFFAOYSA-N;2,4-Imidazolidinedione, 5,5-diphenyl-3-[(phosphonooxy)methyl]-
- CBNumber
- CB3947346
- Molecular Formula
- C16H15N2O6P
- Formula Weight
- 362.27
- MOL File
- 93390-81-9.mol
Caffeine Citrate Property
- Melting point:
- 173-176.5°
- Density
- 1.495±0.06 g/cm3(Predicted)
- pka
- 1.74±0.10(Predicted)
Safety
- Hazardous Substances Data
- 93390-81-9(Hazardous Substances Data)
Caffeine Citrate Chemical Properties,Usage,Production
Description
Cerebyx was launched for the treatment of status epilepticus and for neurosurgery derived seizures. Fosphenytoin is rapidly converted by phosphatases to phenytoin. This compound is readily water soluble thus overcoming an important problem associated with Dilantin.
Originator
Warner-Lambert (USA)
Uses
Anticonvulsant.
Definition
ChEBI: Fosphenytoin is an imidazolidine-2,4-dione.
Manufacturing Process
By action of formaldehyde and hydrochloric acid on 5,5-diphenylhydantoin was
prepared 3-hydroxymethyl-5,5-diphenyl-imidazolidine-2,4-dione which was
converted by action PCl3 to 3-chloromethyl-5,5-diphenyl-imidazolidine-2,4-
dione by action PCl3. Then the chlorine atom was substituted on P(O)(OBz)Ogroup by action of argentum salt of phosphoric acid dibenzyl ester. Removal of
the protecting groups by hydrogenolysis gives the 2,4-imidazolidinedione, 5,5-
diphenyl-3-((phosphonooxy)methyl)- (fosphenytoin).
In practice it is usually used as sodium salt.
brand name
Cerebyx (Parke-Davis).
Therapeutic Function
Antiepileptic, Anticonvulsant
Caffeine Citrate Preparation Products And Raw materials
Raw materials
Preparation Products
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