5-Methyl-1,3-thiazole-2-carboxaldehyde
- Product Name
- 5-Methyl-1,3-thiazole-2-carboxaldehyde
- CAS No.
- 13838-78-3
- Chemical Name
- 5-Methyl-1,3-thiazole-2-carboxaldehyde
- Synonyms
- Methylthiazole-2-Formyl-5-methyl-1,3-thiazole;5-methyl-2-thiazolecarboxaldehyde;5-Methylthiazole-2-carboxaldehyde;2-Thiazolecarboxaldehyde, 5-methyl-;5-methyl-1,3-thiazole-2-carbaldehyde;5-Methyl-1,3-thiazole-2-carboxaldehyde
- CBNumber
- CB3957521
- Molecular Formula
- C5H5NOS
- Formula Weight
- 127.16
- MOL File
- 13838-78-3.mol
5-Methyl-1,3-thiazole-2-carboxaldehyde Property
- Boiling point:
- 236.0℃
- Density
- 1.270
- Flash point:
- 96.5℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- pka
- 0.92±0.10(Predicted)
Safety
- HazardClass
- IRRITANT
- HS Code
- 2934100090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M332278
- Product name
- 5-Methylthiazole-2-carbaldehyde
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 064677
- Product name
- 5-Methyl-1,3-thiazole-2-carbaldehyde
- Packaging
- 500mg
- Price
- $104
- Updated
- 2021/12/16
- Product number
- 064677
- Product name
- 5-Methyl-1,3-thiazole-2-carbaldehyde
- Packaging
- 1g
- Price
- $160
- Updated
- 2021/12/16
- Product number
- 8H70-1-Y8
- Product name
- 5-Methyl-1,3-thiazole-2-carboxaldehyde
- Packaging
- 1g
- Price
- $432
- Updated
- 2021/12/16
- Product number
- 064677
- Product name
- 5-Methyl-1,3-thiazole-2-carbaldehyde
- Packaging
- 5g
- Price
- $494
- Updated
- 2021/12/16
5-Methyl-1,3-thiazole-2-carboxaldehyde Chemical Properties,Usage,Production
Synthesis
3581-89-3
4394-85-8
13838-78-3
GENERAL STEPS: (a) Under argon protection, n-butyllithium (24 mL, 0.06 mol, 2.5 M hexane solution) was dissolved in 50 mL of ether and cooled to -78°C. Subsequently, a solution of 5-methylthiazole (5 g, 0.05 mol) dissolved in 25 mL of ether was added slowly and dropwise. The reaction mixture was stirred continuously at -78°C for 1 hour. Next, a solution of N-formylmorpholine (5.5 mL, 0.055 mol) dissolved in 30 mL of ether was added dropwise over 15 minutes. After addition, the mixture was continued to be stirred at -78°C for 1 hour, followed by warming to 0°-5°C and stirring overnight. Upon completion of the reaction, the reaction mixture was extracted with 4N HCl (4 x 10 mL), the aqueous phases were combined, cooled in an ice bath, and adjusted with sodium bicarbonate solution to pH 9. The aqueous phase was then extracted with ether (4 x 20 mL), the organic phases were combined, dried with magnesium sulfate, and concentrated under reduced pressure. The residue was dried under vacuum to give 4.5 g of 5-methyl-2-thiazolecarboxaldehyde in 70.8% yield.
References
[1] Patent: US5569655, 1996, A
5-Methyl-1,3-thiazole-2-carboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Methyl-1,3-thiazole-2-carboxaldehyde manufacturers
- Product
- 5-methyl-1,3-thiazole-2-carbaldehyde 13838-78-3
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- 98%
- Supply Ability
- Inquiry
- Release date
- 2023-07-12
- Product
- 5-Methyl-1,3-thiazole-2-carboxaldehyde 13838-78-3
- Price
- US $0.00/KG
- Min. Order
- 0.0001KG
- Purity
- 98%min
- Supply Ability
- 500kgs/month
- Release date
- 2022-05-11
- Product
- 5-Methyl-1,3-thiazole-2-carbaldehyde 13838-78-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99.4%
- Supply Ability
- 100 tons
- Release date
- 2022-01-26