N6-Ethyl-2’-O-methyladenosine

Product Name: N6-Ethyl-2’-O-methyladenosine
CAS No.: 157309-11-0
Chemical Name: N6-Ethyl-2’-O-methyladenosine
Synonyms: N6-Ethyl-2’-O-methyladenosine;Adenosine, N-ethyl-2'-O-methyl- (9CI);(2R,3R,4R,5R)-5-(6-(ethylamino)-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol
CBNumber: CB39638449
Molecular Formula: C13H19N5O4
Formula Weight: 309.32
MOL File: 157309-11-0.mol

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N6-Ethyl-2’-O-methyladenosine Property

Boiling point:: 606.1±65.0 °C(Predicted)
Density: 1.61±0.1 g/cm3(Predicted)
pka: 13.15±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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N6-Ethyl-2’-O-methyladenosine Chemical Properties,Usage,Production

Uses

N6-Ethyl-2’-O-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
[2] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

N6-Ethyl-2’-O-methyladenosine Preparation Products And Raw materials

Raw materials

Preparation Products

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N6-Ethyl-2’-O-methyladenosine Suppliers

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157309-11-0, N6-Ethyl-2’-O-methyladenosineRelated Search:

N6-Ethyl-2'-C-methyladenosine N6-Ethyl-2'-deoxyadenosine

N6-Ethyl-2’-O-methyladenosine

Adenosine, N-ethyl-2'-O-methyl- (9CI)

(2R,3R,4R,5R)-5-(6-(ethylamino)-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol

157309-11-0