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N-(4-bromophenyl)-3-phenylpropanamide

Product Name
N-(4-bromophenyl)-3-phenylpropanamide
CAS No.
316146-27-7
Chemical Name
N-(4-bromophenyl)-3-phenylpropanamide
Synonyms
Bedaquiline Impurity C;Brilanestrant Impurity 12;n-(4-bromphenyl)-3-phenylpropanamid;n-(4-bromphenyl)-3-phenylpropanamide;N-(4-Bromophenyl)-benzenepropanamide;N-(4-bromophenyl)-3-phenylpropanamide;Benzenepropanamide, N-(4-bromophenyl)-;N-(4-Bromo-phenyl)-3-phenyl-propionamide
CBNumber
CB3970942
Molecular Formula
C15H14BrNO
Formula Weight
304.18
MOL File
316146-27-7.mol
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N-(4-bromophenyl)-3-phenylpropanamide Property

Boiling point:
473.2±38.0 °C(Predicted)
Density 
1.408±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Most solvents
form 
Solid
pka
13.88±0.70(Predicted)
color 
White
InChI
InChI=1S/C15H14BrNO/c16-13-7-9-14(10-8-13)17-15(18)11-6-12-4-2-1-3-5-12/h1-5,7-10H,6,11H2,(H,17,18)
InChIKey
HGPWLPIFXDCULJ-UHFFFAOYSA-N
SMILES
C1(CCC(NC2=CC=C(Br)C=C2)=O)=CC=CC=C1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B686935
Product name
N-(4-Bromophenyl)-benzenepropanamide
Packaging
500mg
Price
$165
Updated
2021/12/16
TRC
Product number
B686935
Product name
N-(4-Bromophenyl)-benzenepropanamide
Packaging
5g
Price
$1320
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
55116
Product name
N-(4-Bromophenyl)-benzenepropanamide
Packaging
500mg
Price
$650
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0136479
Product name
BENZENEPROPANAMIDE, N-(4-BROMOPHENYL)-
Purity
95.00%
Packaging
500MG
Price
$795.8
Updated
2021/12/16
AK Scientific
Product number
3884AH
Product name
N-(4-Bromophenyl)-3-phenylpropanamide
Packaging
10g
Price
$150
Updated
2021/12/16
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N-(4-bromophenyl)-3-phenylpropanamide Chemical Properties,Usage,Production

Chemical Properties

N-(4-bromophenyl)-3-phenylpropanamide is White Solid

Uses

N-(4-bromophenyl)-3-phenylpropanamide is a reactant used in the preparation of quinoline derivatives as antitubercular agent and antibacterial agents.

Synthesis

106-40-1

645-45-4

316146-27-7

To a solution of 4-bromoaniline (40 g, 0.232 mol) and triethylamine (32 mL) in dichloromethane (200 mL) was slowly added hydrocinnamoyl chloride (37.5 g, 0.223 mol) dropwise at 0 °C. After the dropwise addition was completed, the reaction mixture was stirred at room temperature overnight. After completion of the reaction, the mixture was poured into water and 10% hydrochloric acid solution was added. The white solid slurry formed was stirred for 1 hour under cooling in an ice bath. The solid product was separated by filtration, washed with ether and dried in air to afford N-(4-bromophenyl)-3-phenylpropanamide (62 g, 92% yield).

References

[1] ChemMedChem, 2017, vol. 12, # 2, p. 106 - 119
[2] Chinese Chemical Letters, 2015, vol. 26, # 6, p. 790 - 792
[3] Patent: WO2005/70430, 2005, A1. Location in patent: Page/Page column 34
[4] Patent: WO2007/14885, 2007, A1. Location in patent: Page/Page column 31
[5] Patent: WO2007/14940, 2007, A2. Location in patent: Page/Page column 40-41

N-(4-bromophenyl)-3-phenylpropanamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(4-bromophenyl)-3-phenylpropanamide Suppliers

Jiangsu Chromene New Material Technology Co., Ltd
Tel
15358977508
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lengyan1114@126.com
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China
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Shandong Xuande Pharmaceutical Technology Co. LTD
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18866895588
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0531-82777287
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dingjiaying@shiningpharm.com
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China
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Shanghai Kuanglin Tech LTD Co
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13701867986
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13701867986@163.com
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China
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Nanjing Joyin Pharmachem Co.,Ltd
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025-84670162-814 17354973727
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marketing@joyin.cc
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China
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Shanghai Xianer Chemical Technology Co., Ltd.
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021-021-60556752 15800818924
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3423935586@qq.com
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China Synchem Technology Co.,Ltd.
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+86-0552-4929304 +86-18055277008
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+86-552-4928800
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sales@cnsynchem.com
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China
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J & K SCIENTIFIC LTD.
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86-10-82849933
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jkinfo@jkchemical.com
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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info@hanhongsci.com
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China
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Chemsky(shanghai)International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
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China
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Syntechem Co.,Ltd
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Fax
E-Mail Inquiry
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info@syntechem.com
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China
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12984
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View Lastest Price from N-(4-bromophenyl)-3-phenylpropanamide manufacturers

Jinan Ruitong Biotech Co., Ltd.
Product
n-(4-bromphenyl)-3-phenylpropanamide 316146-27-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1
Release date
2025-08-26
Career Henan Chemical Co
Product
N-(4-bromophenyl)-3-phenylpropanamide 316146-27-7
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
100kg
Release date
2018-12-20