KRIBB 3

Product Name: KRIBB 3
CAS No.: 129414-88-6
Chemical Name: KRIBB 3
Synonyms: 4-Ethyl-5-methoxy-2-[4-(4-methoxyphenyl)-5-isoxazolyl]phenol;Phenol, 4-ethyl-5-methoxy-2-[4-(4-methoxyphenyl)-5-isoxazolyl]-;KRIBB3 (5-(5-Ethyl-2-hydroxy-4-methoxyphenyl)-4-(4-methoxyphenyl)isoxazole);4-ethyl-3-methoxy-6-[4-(4-methoxyphenyl)-2H-isoxazol-5-ylidene]-1-cyclohexa-2,4-dienone;KRIBB3 (5-(5-Ethyl-2-hydroxy-4-methoxyphenyl)-4-(4-methoxyphenyl)isoxazole), Hsp27 inhibitor
CBNumber: CB3972401
Molecular Formula: C19H19NO4
Formula Weight: 325.36
MOL File: 129414-88-6.mol

More

Less

KRIBB 3 Property

Melting point:: 147-148 °C
Boiling point:: 467.5±45.0 °C(Predicted)
Density: 1.181±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO: 25 mM
form: A solid
pka: 8.51±0.48(Predicted)

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22
RIDADR: UN 2811 6.1/PG 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 23973
Product name: KRIBB3
Purity: ≥98%
Packaging: 5mg
Price: $332
Updated: 2024/03/01

TRC

Product number: K660308
Product name: KRIBB3
Packaging: 5mg
Price: $280
Updated: 2021/12/16

AK Scientific

Product number: 1083CE
Product name: Kribb3
Packaging: 5mg
Price: $467
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003091
Product name: 5-(5-ETHYL-2-HYDROXY-4-METHOXYPHENYL)-4-(4-METHOXYPHENYL)ISOXAZOLE
Purity: 95.00%
Packaging: 5MG
Price: $849.97
Updated: 2021/12/16

DC Chemicals

Product number: DC11375
Product name: KRIBB3
Purity: >98%
Packaging: 250mg
Price: $1300
Updated: 2021/12/16

More

Less

KRIBB 3 Chemical Properties,Usage,Production

Uses

Kribb3 is an inhibitor for microtubule. KRIBB3 inhibits the proliferation of cancer cells with GI50 of 0.2-2.5 μM, arrests cell cycle at G2/M phase, and induces apoptosis in HCT-116. Kribb3 exhibits antitumor activity in mouse models[1].

References

[1] Shin KD, et al., KRIBB3, a novel microtubule inhibitor, induces mitotic arrest and apoptosis in human cancer cells. Biochem Pharmacol. 2008 Jan 15;75(2):383-94. DOI:10.1016/j.bcp.2007.08.027

KRIBB 3 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

KRIBB 3 Suppliers

CHINA 14 Switzerland 1 United States 4 Global 19

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
Advantage: 58

Cayman Chemical Company

Tel: 800-364-9897
Email: sales@caymanchem.com
Country: China
ProdList: 6838
Advantage: 58

Santa Cruz Biotechnology Inc

Tel: 021-60936350
Email: scbt@scbt.com
Country: China
ProdList: 6594
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 52923
Advantage: 58

Hangzhou MolCore BioPharmatech Co.,Ltd.

Tel: +86-057181025280; +8617767106207
Fax: 0571-85806285
Email: sales@molcore.com
Country: China
ProdList: 49734
Advantage: 58

129414-88-6, KRIBB 3Related Search:

KRIBB 3 2-(5-ISOXAZOLYL)-4-METHYLPHENOL 5-(4-METHOXYPHENYL)ISOXAZOLE 4-PHENYLISOXAZOLE 4-ETHYL-2-(ISOXAZOL-5-YL)PHENOL 2-(5-ISOXAZOLYL)PHENOL

KRIBB3 (5-(5-Ethyl-2-hydroxy-4-methoxyphenyl)-4-(4-methoxyphenyl)isoxazole)

4-ethyl-3-methoxy-6-[4-(4-methoxyphenyl)-2H-isoxazol-5-ylidene]-1-cyclohexa-2,4-dienone

Phenol, 4-ethyl-5-methoxy-2-[4-(4-methoxyphenyl)-5-isoxazolyl]-

4-Ethyl-5-methoxy-2-[4-(4-methoxyphenyl)-5-isoxazolyl]phenol

KRIBB3 (5-(5-Ethyl-2-hydroxy-4-methoxyphenyl)-4-(4-methoxyphenyl)isoxazole), Hsp27 inhibitor

129414-88-6