ChemicalBook > CAS DataBase List > ABD-F

ABD-F

Product Name
ABD-F
CAS No.
91366-65-3
Chemical Name
ABD-F
Synonyms
ABD-F;ABD-F 4-Fluoro-7-sulfobenzofurazan;4-FLUORO-7-SULFAMOYLBENZOFURAZAN;4-FLUORO-7-SULFAMOYLBENZOFURAZANE;4-FLUORO-7-SULFOAMOYLBENZOFURAZAN;7-Fluoro-4-sulfamoylbenzofurazane;7-FLUOROBENZOFURAZAN-4-SULFONAMIDE;7-Fluoro-4-benzofurazanesulfonamide;7-Fluorobenzofurazane-4-sulfonamide
CBNumber
CB4102238
Molecular Formula
C6H4FN3O3S
Formula Weight
217.18
MOL File
91366-65-3.mol
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ABD-F Property

Melting point:
143-145°C
Boiling point:
408.8±55.0 °C(Predicted)
Density 
1.724±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO: soluble
form 
White to yellow crystalline powder.
pka
9.08±0.30(Predicted)
color 
Off-White to Pale Yellow
BRN 
5035147
Stability:
Light Sensitive
InChI
InChI=1S/C6H4FN3O3S/c7-3-1-2-4(14(8,11)12)6-5(3)9-13-10-6/h1-2H,(H2,8,11,12)
InChIKey
XROXHZMRDABMHS-UHFFFAOYSA-N
SMILES
N1=C2C(F)=CC=C(S(N)(=O)=O)C2=NO1
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Safety

Hazard Codes 
Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36/37/39-24/25
WGK Germany 
3
F 
3-10
Hazard Note 
Irritant
HS Code 
29350090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F3639
Product name
4-Fluoro-7-sulfamoylbenzofurazan
Packaging
10mg
Price
$554
Updated
2025/07/31
Sigma-Aldrich
Product number
F3639
Product name
4-Fluoro-7-sulfamoylbenzofurazan
Packaging
50mg
Price
$1786
Updated
2025/07/31
TCI Chemical
Product number
A5597
Product name
ABD-F [=4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole][HPLC Labeling Reagent for Determination of Thiols]
Purity
>98.0%(N)(T)
Packaging
100mg
Price
$343
Updated
2025/07/31
TCI Chemical
Product number
A5597
Product name
ABD-F [=4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole][HPLC Labeling Reagent for Determination of Thiols]
Purity
>98.0%(N)(T)
Packaging
500mg
Price
$1091
Updated
2025/07/31
TRC
Product number
A629400
Product name
4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole
Packaging
250mg
Price
$695
Updated
2021/12/16
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ABD-F Chemical Properties,Usage,Production

Chemical Properties

Light Yellow Solid

Uses

Highly reactive fluorogenic reagent for the labeling of thiols for HPLC. ABD-F is nonfluorescent until reacted with thiols and therefore can be used to quantitate thiols in solution, as well as thiols separated by HPLC or TLC.

Uses

A water soluble pH dependent bifunctional fluorogenic reagent for the sensitive and specific detection of protein thiols. ABD-F is highly reactive and specific for protein thiols, and its selectivity is superior to that of other sulfhydryl-reactive fluorophores such as fluorescein maleimide, 5-iodoacetamidofluorescein, 5-I-AEDANS, dansylaziridine, and bimane. Fluorescence: max Abs. l = 385nm, max Em. l = 520nm; Molar Abs. > 4.5x103 (ca. 315nm)

Uses

Reagent for fluorimetric assay of thiols.

General Description

4-Fluoro-7-sulfamoylbenzofurazan is a fluorescent reagent, which directly links to the sulfur atom of thiols without a flexible alkyl chain. It is used to detect low molecular thiols using high performance liquid chromatography.

ABD-F Preparation Products And Raw materials

Raw materials

Preparation Products

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ABD-F Suppliers

Americas 1 Belgium 1 Canada 2 China 76 Europe 3 France 2 Germany 7 India 3 Japan 2 Poland 1 Switzerland 4 The Netherlands 1 United Kingdom 8 United States 26 Global 137
Suzhou Ran enzyme Biotechnology Co., Ltd.
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91366-65-3, ABD-FRelated Search:

Glucosamine sulfate abd-A protein ABD Abd-B proteins ABD-MTS 4-Fluorobenzenesulfonamide 4-FLUORO-2,1,3-BENZOXADIAZOLE BENZOFURAZAN ABD-F 4-Fluorothiophenol 4-(N,N-DIMETHYLAMINOSULFONYL)-7-FLUORO-2,1,3-BENZOXADIAZOLE

  • 4-Fluoro-7-sulfobenzofurazan
  • [=4-(AMinosulfonyl)-7-fluoro-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for DeterMination of Thiols]
  • ABD-F&nbsp
  • 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazol
  • 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazol, 98%, derivatization grade
  • 7-Fluorobenzoc1,2,5oxadiazole-4-sulfonamide
  • 4-(AMinosulfonyl)-7-fluoro-2,1,3-benzoxadiazol, derivatization grade
  • ABD-F
  • 7-FLUORO-2,1,3-BENZOXADIAZOLE-4-SULFONAMIDE
  • 7-FLUOROBENZOFURAZAN-4-SULFONAMIDE
  • 7-FLUOROBENZ-2-OXA-1,3-DIAZOLE-4-SULFONAMIDE
  • 4-FLUORO-7-AMINOSULFONYLBENZOFURAZAN
  • 4-FLUORO-7-SULFAMOYLBENZOFURAZAN
  • 4-FLUORO-7-SULFAMOYLBENZOFURAZANE
  • 4-FLUORO-7-SULFOAMOYLBENZOFURAZAN
  • 4-(AMINOSULFONYL)-7-FLUORO-2,1,3-BENZOXADIAZOLE
  • 4-(AMINOSULFONYL)-7-FLUOROBENZOFURAZANE
  • 4-(AMINOSULPHONYL)-7-FLUORO-2,1,3-BENZOXADIAZOLE
  • 4-FLUORO-7-SULFAMOYLBENZOFURAZAN, FOR FL UORESCENCE
  • 7-Fluorobenzofurazan-4-sulfonamide,98%
  • 7-Fluoro-2,1,3-benzoxadiazole-4-sulphonamide
  • 7-Fluoro-4-sulfamoylbenzofurazane
  • 7-FLUOROBENZOFURAZAN-4-SULFONAMIDE 98%
  • 4-(AMINOSULFONYL)-7-FLUORO-2,1,3-DENZOXADIAZOLE
  • 2,1,3-BENZOXADIAZOLE-4-SULFONAMIDE, 7-FLUORO-
  • ABD-F [=4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for Determination of Thiols]
  • 4-(Aminosulfonyl)-7-fluorobenzofurazane, 7-Fluoro-2,1,3-benzoxadiazole-4-sulfonamide, 7-Fluorobenzofurazan-4-sulfonamide, ABD-F
  • 4-Fluoro-2,1,3-benzoxadiazole-7-sulfonamide
  • 7-Fluoro-4-benzofurazanesulfonamide
  • 7-Fluorobenzofurazane-4-sulfonamide
  • ABD-F [=4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole]
  • ABD-F [=4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole][HPLC Labeling Reagent for Determination of Thiols]&gt
  • 4-Fluoro-7-sulfamoylbenzofurazan (ABD-F)
  • 7-Fluoro-benzofurazane-4-sulfonic acid amide
  • ABD-F, Fluorogenic reagent for thiol labeling
  • 91366-65-3
  • C6H4FN3O3S
  • Derivatization agents
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  • Other Fluorescent Labels
  • Luminescent Compounds/Detection
  • Fluorescent Probes, Labels, Particles and Stains
  • Fluorescent Labels
  • Chemical and pharmaceutical intermediates
  • pharmaceutical intermediates
  • Analytical Chemistry
  • Fluorescence Detection (HPLC Labeling Reagents)
  • HPLC Labeling Reagents
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  • Fluorescent Labels & Indicators
  • MTS & Sulfhydryl Active Reagents
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