H-LEU-NH2

Product Name: H-LEU-NH2
CAS No.: 687-51-4
Chemical Name: H-LEU-NH2
Synonyms: L-Leu-NH2;H-LEU-NH2;LEUCINE-NH2;leucinamide;L-LEUCINE AMIDE;L-Leucine amide≥ 98% (HPLC);H-Leu-NH₂;(S)-2-amino-4-methylvaleramide;(S)-2-Amino-4-methylpentanamide;(2S)-2-amino-4-methyl-valeramide
CBNumber: CB4104520
Molecular Formula: C6H14N2O
Formula Weight: 130.19
MOL File: 687-51-4.mol

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H-LEU-NH2 Property

Melting point:: 84-85 °C(Solv: benzene (71-43-2); ethanol (64-17-5)(10:1))
Boiling point:: 250.9±23.0 °C(Predicted)
Density: 0.980±0.06 g/cm3(Predicted)
storage temp.: -15°C
form: solid
pka: 16.08±0.50(Predicted)
InChI: InChI=1S/C6H14N2O/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H2,8,9)/t5-/m0/s1
InChIKey: FORGMRSGVSYZQR-YFKPBYRVSA-N
SMILES: C(N)(=O)[C@@H](N)CC(C)C
EPA Substance Registry System: Pentanamide, 2-amino-4-methyl-, (2S)- (687-51-4)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS003478
Product name: H-Leu-NH2
Purity: AldrichCPR
Packaging: 250 mg
Price: $73.1
Updated: 2025/07/31

TRC

Product number: L330808
Product name: H-Leu-NH2
Packaging: 1g
Price: $75
Updated: 2021/12/16

TRC

Product number: L330808
Product name: H-Leu-NH2
Packaging: 250mg
Price: $55
Updated: 2021/12/16

Usbiological

Product number: 281454
Product name: L-Leucine amide
Packaging: 5g
Price: $363
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0004606
Product name: L-LEUCINE AMIDE
Purity: 95.00%
Packaging: 5MG
Price: $498.43
Updated: 2021/12/16

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H-LEU-NH2 Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Definition

ChEBI: An amino acid amide that is L-leucine in which the carboxy OH group is replaced by NH2.

Synthesis

2666-93-5

687-51-4

The general procedure for the synthesis of (S)-2-amino-4-methylpentanamide from L-leucine methyl ester was as follows: to a 250 mL 24/40 interface single neck round bottom flask fitted with a stirrer was added a 10 mL methanol solution of 8.1 g (0.056 mol) of L-leucine methyl ester under nitrogen protection. Subsequently, 40 mL of a 28-30% solution of ammonia was added slowly and dropwise over about 20 minutes. The reaction was stirred continuously under nitrogen atmosphere for 72 hours. Upon completion of the reaction, the solution was concentrated under vacuum at a pressure of 5-10 mmHg using a rotary evaporator (Model: 13uchi Rotovapor R-124, Manufacturer: I3UCHI Seikagaku Corp., Switzerland). The concentrated residue was dissolved in 250 mL of water and extracted with dichloromethane (5 × 500 mL). The organic layers were combined into a 4 L conical flask and dried by adding anhydrous sodium sulfate. After filtration to remove the desiccant, the organic phase was again concentrated using a rotary evaporator at a pressure of 5-10 mmHg, resulting in 5 g of the white solid product (S)-2-amino-4-methylpentanamide.

References

[1] Patent: US2017/57911, 2017, A1. Location in patent: Paragraph 0060; 0127; 0129

H-LEU-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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H-LEU-NH2 Suppliers

China 63 India 1 Japan 1 United States 7 Global 72

Wuxi maimo topp biotechnology co., LTD

Tel: 15061806929
Email: linda-fu@mimotopes.cn
Country: China
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Capot Chemical Co., Ltd

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Shanghai Hanhong Scientific Co.,Ltd.

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Chemsky (shanghai) International Co.,Ltd

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Email: shchemsky@sina.com
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9ding chemical ( Shanghai) Limited

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Wuxi Zhongkun Biochemical Technology Co., Ltd.

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Chengdu Chuangkecheng Biological Technology Co., Ltd.

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Shanghai GL Peptide Ltd.

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Wuxi Asia Peptide Biotechnology Limited Company

Tel: 0510-83583050 13771062561
Fax: 0510-83583039
Email: willsun@peptide-search.com
Country: China
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View Lastest Price from H-LEU-NH2 manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: L-Leucinamide 687-51-4
Price: US $0.10-10.00/KG
Min. Order: 0.10000000149011612KG
Purity: 98%
Supply Ability: 200TONS
Release date: 2025-08-15

687-51-4, H-LEU-NH2Related Search:

L-LEUCYL-L-ALANINE TYRAMINE HYDROCHLORIDE L-Leucinamide hydrochloride AC-LEU-NH2 H-LEU-SER-NH2 HCL Z-LEU-MET-OH H-LEU-4M-BETANA HCL L-LEUCINE BETA-NAPHTHYLAMIDE HYDROCHLORIDE Z-L-LEUCYL-L-ALANINE Z-ALA-LEU-NH2 H-GLY-LEU-GLY-LEU-OH Z-LEU-ILE-OH H-LEU-SER-OH N-CBZ-LEU-LEU METHYL ESTER H-GLY-LEU-GLY-GLY-OH H-LEU-GLU-OH Z-LEU-GLY-OH L-LEUCYL-L-TYROSINE

leucinamide

(S)-2-Amino-4-methylpentanamide

L-Leu-NH2

(2S)-2-amino-4-methylpentanamide

(2S)-2-amino-4-methyl-valeramide

(2S)-2-azanyl-4-methyl-pentanamide

L-Leucine amide≥ 98% (HPLC)

L-LEUCINE AMIDE

(S)-2-amino-4-methylvaleramide

H-LEU-NH2

LEUCINE-NH2

4-chloro-2-methyl-1-cyclohexanecarboxylic acid

Pentanamide, 2-amino-4-methyl-, (2S)-

H-Leu-NH2

687-51-4