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Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI)

Product Name
Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI)
CAS No.
3622-38-6
Chemical Name
Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI)
Synonyms
2-Chloro-5-nitrobenzothiazole;2-chloro-5-nitrobenzo[d]thiazole;Benzothiazole, 2-chloro-5-nitro-;2-chloro-5-nitro-1,3-benzothiazole;Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI)
CBNumber
CB41050109
Molecular Formula
C7H3ClN2O2S
Formula Weight
214.63
MOL File
3622-38-6.mol
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Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI) Property

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
Appearance
Off-white to light yellow Solid
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Safety

HS Code 
29342000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C385743
Product name
2-Chloro-5-nitrobenzothiazole
Packaging
50mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC142207
Product name
2-Chloro-5-nitrobenzo[d]thiazole
Packaging
100mg
Price
$65
Updated
2021/12/16
ChemScene
Product number
CS-W006601
Product name
2-Chloro-5-nitrobenzo[d]thiazole
Packaging
1g
Price
$86
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC142207
Product name
2-Chloro-5-nitrobenzo[d]thiazole
Packaging
250mg
Price
$130
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC142207
Product name
2-Chloro-5-nitrobenzo[d]thiazole
Packaging
500mg
Price
$225
Updated
2021/12/16
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Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI) Chemical Properties,Usage,Production

Synthesis

58759-63-0

3622-38-6

General method: GP3-1: A solution of 5-nitrobenzothiazole-2-thiol (1.0 eq.) with potassium ethylxanthate (1.2 eq. or 2.2 eq., 2.2 eq. is usually used) in 10 volumes of anhydrous DMF was heated for 4 hr. at 100 °C or 120 °C in a nitrogen atmosphere. The reaction progress was monitored by TLC. Upon completion of the reaction, the mixture was cooled to room temperature, diluted with water (10 volumes), and neutralized with 1 M HCl solution to pH 5. The precipitate formed was collected by filtration, washed with water, and dried using a rotary evaporator followed by vacuum drying.GP3-2: Thionyl chloride (SO2Cl2, 1 volume) was slowly added to a mixture of 2-mercaptobenzothiazolyl chloride (2.2 eq.) containing 2-mercaptobenzothiazole (1.0 equivalent) in 2 volumes of anhydrous DCM solution. The mixture was stirred at room temperature for 1 h. The reaction progress was monitored by TLC. After the raw materials were consumed, the reaction mixture was diluted with 30 volumes of ether and the reaction was quenched by careful addition of water. Stirring was continued for 1 hour to ensure complete consumption of thionyl chloride and product release. The organic layer was separated, neutralized with saturated NaHCO3 solution, dried over Na2SO4 and subsequently purified by silica gel column chromatography to give the pure product. The final product was characterized by LC-MS and NMR.

References

[1] Journal of Heterocyclic Chemistry, 2005, vol. 42, # 4, p. 727 - 730
[2] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 24, p. 7661 - 7670
[3] Patent: WO2016/207785, 2016, A1. Location in patent: Page/Page column 45; 46

Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI) Suppliers

J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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China
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Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
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China Langchem Inc.
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Jinan HM Medical Technology Co., Ltd.
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View Lastest Price from Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI) manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI) 3622-38-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-18
Shaanxi Dideu Medichem Co. Ltd
Product
2-Chloro-5-nitrobenzo[d]thiazole 3622-38-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20t
Release date
2024-07-15
Shanghai Rlavie Technology Co ltd
Product
2-Chloro-5-nitrobenzothiazole 3622-38-6
Price
US $0.00-0.00/kg
Min. Order
0.001kg
Purity
98%min
Supply Ability
100kgs/month
Release date
2022-05-09

3622-38-6, Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI)Related Search:


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  • Benzothiazole, 2-chloro-5-nitro-
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  • 2-Chloro-5-nitrobenzothiazole
  • 2-chloro-5-nitro-1,3-benzothiazole
  • 3622-38-6
  • BENZOTHIAZOLE