NPX809

ChemicalBook > CAS DataBase List > NPX809

Product Name: NPX809
CAS No.: 1693734-80-3
Chemical Name: NPX809
Synonyms: NPX800;NPX809;NXP-800;NPX800, 10 mM in DMSO;NXP-800,Heat shock proteins,NXP 800,inhibit,NXP800,CCT-361814,HSP,Inhibitor,CCT 361814;6-Quinolinecarboxamide, N-[5-[[(2,3-dihydro-1,4-benzodioxin-6-yl)carbonyl]amino]-2-fluorophenyl]-2-[(4-ethyl-1-piperazinyl)methyl]-
CBNumber: CB410819294
Molecular Formula: C32H32FN5O4
Formula Weight: 569.63
MOL File: 1693734-80-3.mol

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NPX809 Property

Boiling point:: 612.2±55.0 °C(Predicted)
Density: 1.347±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 100 mg/mL (175.55 mM; Need ultrasonic)
pka: 11.46±0.70(Predicted)
form: Solid
color: Light yellow to green yellow

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Hazard and Precautionary Statements (GHS)

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NPX809 Chemical Properties,Usage,Production

Biological Activity

NXP800 (CCT361814) is a potent heat shock factor 1 (HSF1) inhibitor. NXP800 has the potential for cancer research[1]. NXP800 (example 169) inhibits U20S cells viability (IC50=0.056 μM)[1].

References

[1]. Keith Jones, et al. Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1. WO2015049535A1.

NPX809 Preparation Products And Raw materials

Raw materials

Preparation Products

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1693734-80-3, NPX809Related Search:

NPX809

NPX800

NXP-800

NXP-800,Heat shock proteins,NXP 800,inhibit,NXP800,CCT-361814,HSP,Inhibitor,CCT 361814

6-Quinolinecarboxamide, N-[5-[[(2,3-dihydro-1,4-benzodioxin-6-yl)carbonyl]amino]-2-fluorophenyl]-2-[(4-ethyl-1-piperazinyl)methyl]-

NPX800, 10 mM in DMSO

1693734-80-3