2-Oxaspiro[4.5]dec-8-ene-1,7-dione, 4,6-dihydroxy-10-methyl-3-methylene-, (4R,5R,6R,10R)-rel-(-)- (9CI)
- Product Name
- 2-Oxaspiro[4.5]dec-8-ene-1,7-dione, 4,6-dihydroxy-10-methyl-3-methylene-, (4R,5R,6R,10R)-rel-(-)- (9CI)
- CAS No.
- 496926-08-0
- Chemical Name
- 2-Oxaspiro[4.5]dec-8-ene-1,7-dione, 4,6-dihydroxy-10-methyl-3-methylene-, (4R,5R,6R,10R)-rel-(-)- (9CI)
- Synonyms
- Massarigenin C;2-Oxaspiro[4.5]dec-8-ene-1,7-dione, 4,6-dihydroxy-10-methyl-3-methylene-, (4R,5R,6R,10R)-rel-(-)-;2-Oxaspiro[4.5]dec-8-ene-1,7-dione, 4,6-dihydroxy-10-methyl-3-methylene-, (4R,5R,6R,10R)-rel-(-)- (9CI)
- CBNumber
- CB41088412
- Molecular Formula
- C11H12O5
- Formula Weight
- 224.21
- MOL File
- 496926-08-0.mol
2-Oxaspiro[4.5]dec-8-ene-1,7-dione, 4,6-dihydroxy-10-methyl-3-methylene-, (4R,5R,6R,10R)-rel-(-)- (9CI) Property
- storage temp.
- Store at -20°C
- solubility
- Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
- form
- A solid
N-Bromosuccinimide Price
- Product number
- 29772
- Product name
- Massarigenin C
- Packaging
- 1mg
- Price
- $263
- Updated
- 2024/03/01
2-Oxaspiro[4.5]dec-8-ene-1,7-dione, 4,6-dihydroxy-10-methyl-3-methylene-, (4R,5R,6R,10R)-rel-(-)- (9CI) Chemical Properties,Usage,Production
Description
Massarigenin C is a fungal metabolite that has been found in M. flavorosea and has enzyme inhibitory activities. Massarigenin C inhibits neuraminidase in vitro (IC50 = 4.15 μM). It is also an inhibitor of yeast α-glucosidase (IC50 = 1.25 mM). It reduces the postprandial peak in blood glucose levels in an oral sucrose tolerance test in normo- and hyperglycemic mice when administered at doses of 3.2, 10, and 31.6 mg/kg.
Uses
Massarigenin C is a compound that can be isolated from Massarina tunicata. Massarigenin C has inhibitory activity against Bacillus subtilis (ATCC 6051)[1].
References
[1] Oh H, et al. New bioactive rosigenin analogues and aromatic polyketide metabolites from the freshwater aquatic fungus Massarina tunicata. J Nat Prod. 2003 Jan;66(1):73-9. DOI:10.1021/np020342d
2-Oxaspiro[4.5]dec-8-ene-1,7-dione, 4,6-dihydroxy-10-methyl-3-methylene-, (4R,5R,6R,10R)-rel-(-)- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
2-Oxaspiro[4.5]dec-8-ene-1,7-dione, 4,6-dihydroxy-10-methyl-3-methylene-, (4R,5R,6R,10R)-rel-(-)- (9CI) Suppliers
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