H-LYS-GLN-ALA-GLY-ASP-VAL-OH
- Product Name
- H-LYS-GLN-ALA-GLY-ASP-VAL-OH
- CAS No.
- 80755-87-9
- Chemical Name
- H-LYS-GLN-ALA-GLY-ASP-VAL-OH
- Synonyms
- KQAGDV;LYS-GLN-ALA-GLY-ASP-VAL;Fibrinogen γ-chain fragmen;Fibrinogen γ-chain fragment;H-LYS-GLN-ALA-GLY-ASP-VAL-OH;L-Valine, L-lysyl-L-glutaminyl-L-alanylglycyl-L-α-aspartyl-
- CBNumber
- CB4109969
- Molecular Formula
- C25H44N8O10
- Formula Weight
- 616.66
- MOL File
- 80755-87-9.mol
H-LYS-GLN-ALA-GLY-ASP-VAL-OH Property
- storage temp.
- -20°C
- form
- powder
- color
- white to off-white
- Sequence
- Lys-Gln-Ala-Gly-Asp-Val
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- PEP0004048
- Product name
- LYS-GLN-ALA-GLY-ASP-VAL
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $614.74
- Updated
- 2021/12/16
H-LYS-GLN-ALA-GLY-ASP-VAL-OH Chemical Properties,Usage,Production
Uses
Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α2bβ3 integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs)[1][2].
Definition
ChEBI: Lys-Gln-Ala-Gly-Asp-Val is an oligopeptide.
Biochem/physiol Actions
Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is a cell adhesion peptide used to study adhesion of platelets to neutrophils via the integrin glycoproteins gpIIb/IIIa.
References
[1] Dong CL, et al. The cytocompatability of polyhydroxyalkanoates coated with a fusion protein of PHA repressor protein (PhaR) and Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) polypeptide. Biomaterials. 2012 Mar;33(9):2593-9. DOI:10.1016/j.biomaterials.2011.12.020
[2] Mann BK, et al. Tethered-TGF-beta increases extracellular matrix production of vascular smooth muscle cells. Biomaterials. 2001 Mar;22(5):439-44. DOI:10.1016/s0142-9612(00)00196-4
H-LYS-GLN-ALA-GLY-ASP-VAL-OH Preparation Products And Raw materials
Raw materials
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