6-Bromo-3-nitro-4-quinolinol
- Product Name
- 6-Bromo-3-nitro-4-quinolinol
- CAS No.
- 853908-50-6
- Chemical Name
- 6-Bromo-3-nitro-4-quinolinol
- Synonyms
- 6-BroMo-3-nitro-4-quinoli...;6-Bromo-3-nitro-4-quinolinol;6-Bromo-3-nitro-quinolin-4-ol;4-Quinolinol, 6-broMo-3-nitro-;6-Brom-4-hydroxy-3-nitroquinoline;6-bromo-3-nitro-1H-quinolin-4-one;6-Bromo-4-hydroxy-3-nitroquinoline;3-Nitro-4-hydroxy-6-broMoquinoline;6-BroMo-3-nitro-4-hydroxy-quinoline
- CBNumber
- CB41114104
- Molecular Formula
- C9H5BrN2O3
- Formula Weight
- 269.05
- MOL File
- 853908-50-6.mol
6-Bromo-3-nitro-4-quinolinol Property
- Boiling point:
- 389.3±37.0 °C(Predicted)
- Density
- 1.878±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- -0.53±0.50(Predicted)
- Appearance
- Light brown to brown Solid
- InChI
- InChI=1S/C9H5BrN2O3/c10-5-1-2-7-6(3-5)9(13)8(4-11-7)12(14)15/h1-4H,(H,11,13)
- InChIKey
- AMKJVYOALDEARM-UHFFFAOYSA-N
- SMILES
- N1C2C(=CC(Br)=CC=2)C(O)=C([N+]([O-])=O)C=1
Safety
- HS Code
- 2933499090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B698063
- Product name
- 6-Bromo-3-nitro-4-quinolinol
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B698063
- Product name
- 6-Bromo-3-nitro-4-quinolinol
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 074433
- Product name
- 6-Bromo-3-nitro-4-quinolinol
- Purity
- 95+%
- Packaging
- 5g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 4H54-9-04
- Product name
- 6-Bromo-3-nitro-4-quinolinol
- Purity
- 95%
- Packaging
- 5G
- Price
- $75
- Updated
- 2021/12/16
- Product number
- OR301107
- Product name
- 6-Bromo-3-nitro-4-quinolinol
- Packaging
- 5g
- Price
- $79
- Updated
- 2021/12/16
6-Bromo-3-nitro-4-quinolinol Chemical Properties,Usage,Production
Uses
6-Bromo-4-hydroxy-3-nitroquinoline salt is a quinoline derivative with certain alkalinity, which can be used as an intermediate in organic synthesis and pesticide chemistry for the synthesis of bioactive molecules, drug molecules and pesticides.
Synthesis
1201643-75-5
853908-50-6
5-Bromo-2-(2-nitrovinylamino)benzoic acid (25 g, 87 mmol) was used as starting material, which was mixed with acetic anhydride (10.5 mL, 104 mmol) in acetic acid anhydride (112 mL, 1185 mmol), and the reaction was stirred for 3 hr at 120° C. The reaction was completed by filtration. After completion of the reaction, the precipitate was collected by filtration and washed with acetic acid until the filtrate was colorless. The precipitate was subsequently washed with water and dried to give the target product 6-bromo-4-hydroxy-3-nitroquinoline. Yield: 15 g (64%). The structure of the product was confirmed by 1H NMR (CDCl3, 500MHz): δ 9.275 (s, 1H), 8.611-8.615 (d, 1H, J = 2Hz), 8.100-8.118 (d, 1H, J = 9Hz), 8.026-8.048 (dd, 1H, J = 8.5Hz, 2Hz).
References
[1] Patent: WO2011/1212, 2011, A1. Location in patent: Page/Page column 37-38
[2] Patent: WO2009/155527, 2009, A2. Location in patent: Page/Page column 141
[3] MedChemComm, 2016, vol. 7, # 2, p. 297 - 310
[4] Patent: WO2008/64093, 2008, A2. Location in patent: Page/Page column 17
[5] Journal of Medicinal Chemistry, 2017, vol. 60, # 14, p. 6337 - 6352
6-Bromo-3-nitro-4-quinolinol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-Bromo-3-nitro-4-quinolinol manufacturers
- Product
- 6-Bromo-3-nitro-4-quinolinol 853908-50-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-07-10
- Product
- 6-Bromo-3-nitro-4-quinolinol 853908-50-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 2000tons
- Release date
- 2019-12-31
- Product
- 6-Bromo-3-nitro-4-quinolinol 853908-50-6
- Price
- US $9.00/KG
- Min. Order
- 1KG
- Purity
- 99.9
- Supply Ability
- 1 ton
- Release date
- 2024-08-21