ChemicalBook > CAS DataBase List > N-Boc-3-azetidine acetic acid
N-Boc-3-azetidine acetic acid
- Product Name
- N-Boc-3-azetidine acetic acid
- CAS No.
- 183062-96-6
- Chemical Name
- N-Boc-3-azetidine acetic acid
- Synonyms
- 1-Boc-3-azetidineacetic a...;N-BOC-3-AZETIDINE ACETIC ACID;1-Boc-3-azetidine acetic acid;2-(1-(boc)azetidin-3-yl)acetic acid;Aceticacid,2-amino-8-imino-,ethylester;[1-(tert-Butoxycarbonyl)azetidin-3-yl]acetic acid;3-Azetidineacetic acid, 1-[(1,1-diMethylethoxy)carbonyl]-;2-(1-tert-Butoxycarbonylazetidin-3-yl)acetic acid - [B0062];2-[1-[(2-methylpropan-2-yl)oxycarbonyl]azetidin-3-yl]acetic acid
- CBNumber
- CB41116698
- Molecular Formula
- C10H17NO4
- Formula Weight
- 215.25
- MOL File
- 183062-96-6.mol
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N-Boc-3-azetidine acetic acid Property
- Melting point:
- 118 °C
- Boiling point:
- 341.6±15.0 °C(Predicted)
- Density
- 1.186±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 4.58±0.10(Predicted)
- color
- White to Orange to Green
- InChI
- InChI=1S/C10H17NO4/c1-10(2,3)15-9(14)11-5-7(6-11)4-8(12)13/h7H,4-6H2,1-3H3,(H,12,13)
- InChIKey
- VEFHUWJIRFTGRB-UHFFFAOYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CC(CC(O)=O)C1
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
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N-Bromosuccinimide Price
TCI Chemical
- Product number
- B6013
- Product name
- 2-[1-(tert-Butoxycarbonyl)azetidin-3-yl]acetic Acid
- Packaging
- 1G
- Price
- $43
- Updated
- 2025/07/31
TCI Chemical
- Product number
- B6013
- Product name
- 2-[1-(tert-Butoxycarbonyl)azetidin-3-yl]acetic Acid
- Packaging
- 5G
- Price
- $108
- Updated
- 2025/07/31
TRC
- Product number
- T135605
- Product name
- 2-(1-(tert-Butoxycarbonyl)azetidin-3-yl)acetic acid
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
Synthonix
- Product number
- B0062
- Product name
- 2-(1-(tert-Butoxycarbonyl)azetidin-3-yl)acetic acid
- Purity
- 97.0%
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
Chem-Impex
- Product number
- 42583
- Product name
- 2-[1-(tert-Butoxycarbonyl)azetidin-3-yl]aceticacid,≥98%(GC)
- Purity
- ≥98%(GC)
- Packaging
- 1G
- Price
- $36.98
- Updated
- 2021/12/16
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N-Boc-3-azetidine acetic acid Chemical Properties,Usage,Production
Synthesis
158602-35-8
183062-96-6
General procedure for the synthesis of N-Boc-3-azetidineacetic acid from tert-butyl 3-(2-ethoxy-2-oxoethyl)azetidine-1-carboxylate: lithium hydroxide (862 mg, 36.0 mmol) was added to tert-butyl 3-(2-ethoxy-2-oxoethyl)azetidine-1-carboxylate (7.30 g, 30.0 mmol) in a tetrahydrofuran ( 40 mL) and water (10 mL) in a mixed solution of tetrahydrofuran (40 mL) and water (10 mL) and the reaction mixture was stirred at 20 °C for 2 hours. The pH of the reaction mixture was adjusted to 4 by addition of 1 M aqueous hydrochloric acid, followed by extraction with ethyl acetate (3 x 100 mL). The organic layers were combined, washed sequentially with water (100 mL) and saturated aqueous sodium chloride (100 mL), dried over anhydrous sodium sulfate, filtered, and concentrated under reduced pressure to afford N-Boc-3-azetidineacetic acid as a white solid. Yield: 6.0 g, 28 mmol, 93% yield.1H NMR (400 MHz, CD3OD) δ 4.06 (dd, J = 8.5, 8.3 Hz, 2H), 3.61 (dd, J = 8, 6 Hz, 2H), 2.94-2.82 (m, 1H), 2.62 (d, J = 7.8 Hz, 2H), 1.43 (s, 9H) .
References
[1] Patent: WO2018/2760, 2018, A1. Location in patent: Page/Page column 98
N-Boc-3-azetidine acetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N-Boc-3-azetidine acetic acid manufacturers
Career Henan Chemical Co
- Product
- N-Boc-3-azetidine acetic acid 183062-96-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kgs
- Release date
- 2020-03-05
Career Henan Chemical Co
- Product
- N-Boc-3-azetidine acetic acid 183062-96-6
- Price
- US $3.00/KG
- Min. Order
- 3KG
- Purity
- 98%
- Supply Ability
- 1kg,5kg,100kg
- Release date
- 2019-08-26
183062-96-6, N-Boc-3-azetidine acetic acidRelated Search:
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