3-Methyl-quinoxaline-2-carboxylic Acid
- Product Name
- 3-Methyl-quinoxaline-2-carboxylic Acid
- CAS No.
- 74003-63-7
- Chemical Name
- 3-Methyl-quinoxaline-2-carboxylic Acid
- Synonyms
- MQCA;RCG-210;RCG-210, MQCA;MQCA Standard;Valine Impurity 62;MQCA Solution, 1000ppm;Carbadox Impurity 1 (MQCA);3-Methyl-2-quinoxalinecarboxylic Acid;2-Quinoxalinecarboxylic acid, 3-methyl-;3-Methylquinoxaline-2-carboxylic Acid solution
- CBNumber
- CB41175765
- Molecular Formula
- C10H8N2O2
- Formula Weight
- 188.18
- MOL File
- 74003-63-7.mol
3-Methyl-quinoxaline-2-carboxylic Acid Property
- Melting point:
- 168-170°C
- Boiling point:
- 347.1±37.0 °C(Predicted)
- Density
- 1.355±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMF: 25 mg/mL; DMSO: 30 mg/mL; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/mL; Ethanol: 25 mg/mL
- form
- Solid
- pka
- 2.37±0.30(Predicted)
- color
- Brown to dark brown
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 32862
- Product name
- 3-Methyl-2-quinoxalinecarboxylic acid
- Purity
- VETRANAL
- Packaging
- 50mg
- Price
- $914
- Updated
- 2025/07/31
- Product number
- 25664
- Product name
- 3-Methylquinoxaline-2-carboxylic Acid
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $89
- Updated
- 2024/03/01
- Product number
- 25664
- Product name
- 3-Methylquinoxaline-2-carboxylic Acid
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $168
- Updated
- 2024/03/01
- Product number
- 25664
- Product name
- 3-Methylquinoxaline-2-carboxylic Acid
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $395
- Updated
- 2024/03/01
- Product number
- 25664
- Product name
- 3-Methylquinoxaline-2-carboxylic Acid
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $744
- Updated
- 2024/03/01
3-Methyl-quinoxaline-2-carboxylic Acid Chemical Properties,Usage,Production
Description
3-Methylquinoxaline-2-carboxylic acid (MQCA) is a major metabolite of olaquindox, an antibiotic and swine growth regulator. It induces cell cycle arrest at the S phase and is toxic to Chang liver cells in a concentration- and time-dependent manner. MQCA has been used as a marker of olaquindox use in livestock applications.
Chemical Properties
Yellow Solid
Uses
A metabolite of Carbadox and Olaquindox
Uses
A Carbadox and Olaquindox metabolite.
Synthesis
61522-54-1
74003-63-7
Methyl 3-methylquinoxaline-2-carboxylate (0.20 g, 0.99 mmol) was used as a raw material and dissolved in a solvent mixture of methanol (8 mL) and 2N sodium hydroxide solution (2 mL). The reaction mixture was stirred at room temperature for 30 min and then concentrated to about 1/3 of the original volume by rotary evaporator.Subsequently, the pH was adjusted to acidic with 1N hydrochloric acid solution and extracted with ethyl acetate. The organic phases were combined, washed sequentially with water and saturated saline, and dried over anhydrous magnesium sulfate. After filtration, the filtrate was concentrated by rotary evaporation to obtain a solid product, which was finally dried under high vacuum to give 3-methylquinoxaline-2-carboxylic acid (0.16 g, 87% yield).
References
[1] Patent: US2005/43292, 2005, A1. Location in patent: Page/Page column 12
[2] Patent: CN108440425, 2018, A. Location in patent: Paragraph 0084-0086
3-Methyl-quinoxaline-2-carboxylic Acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-Methyl-quinoxaline-2-carboxylic Acid Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- +86 21 61551611
- Fax
- +86 21 50676805
- Country
- China
- ProdList
- 9891
- Advantage
- 58
- Tel
- 400-6206333 13167063860
- Fax
- 021-50323701
- anhua.mao@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
- Tel
- 021-021-33632979 15002134094
- Fax
- 021-33632979
- marketing@targetmol.com
- Country
- China
- ProdList
- 7783
- Advantage
- 58
- Tel
- 027-88063677 18971314022;
- Fax
- 027-88063656
- sales@3bsc.com
- Country
- China
- ProdList
- 294
- Advantage
- 58
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 0755-0755-66853366 13670046396
- Fax
- 0755-28363542
- sales@chem-strong.com
- Country
- China
- ProdList
- 18333
- Advantage
- 56
- Tel
- 13693449011
- Fax
- -
- 83948782@qq.com
- Country
- China
- ProdList
- 92
- Advantage
- 50
- Tel
- 022-6537-8550 15522853686
- Fax
- 022-2532-9655
- sales@altasci.com.cn
- Country
- China
- ProdList
- 4511
- Advantage
- 55