ChemicalBook > CAS DataBase List > O-Desmethyl Metoprolol

O-Desmethyl Metoprolol

Product Name
O-Desmethyl Metoprolol
CAS No.
62572-94-5
Chemical Name
O-Desmethyl Metoprolol
Synonyms
H 105/22;SL 80-008;SL 80-0088;Metoprolol-8;Betaxolol-001;O-demethylmetoprolo;Metoprolol-EP-Imp-H;Betaxolol Impurity 1;Betaxolol Impurity B;Metoprolol Impurity 8
CBNumber
CB41176641
Molecular Formula
C14H23NO3
Formula Weight
253.34
MOL File
62572-94-5.mol
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O-Desmethyl Metoprolol Property

Melting point:
70-720C
Boiling point:
424.6±40.0 °C(Predicted)
Density 
1.085±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly, Sonicated), Methanol (Slightly)
form 
Solid
pka
13.88±0.20(Predicted)
color 
White to Off-White
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Safety

Toxicity
LD50 intravenous in dog: 150mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21787
Product name
O-Desmethyl Metoprolol
Purity
≥95%
Packaging
1mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
21787
Product name
O-Desmethyl Metoprolol
Purity
≥95%
Packaging
5mg
Price
$216
Updated
2024/03/01
Cayman Chemical
Product number
21787
Product name
O-Desmethyl Metoprolol
Purity
≥95%
Packaging
10mg
Price
$380
Updated
2024/03/01
Usbiological
Product number
008628
Product name
O-Desmethyl Metoprolol
Packaging
5mg
Price
$425
Updated
2021/12/16
TRC
Product number
D292073
Product name
O-DesmethylMetoprolol
Packaging
50mg
Price
$1155
Updated
2021/12/16
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O-Desmethyl Metoprolol Chemical Properties,Usage,Production

Description

O-Desmethyl metoprolol is the major active metabolite of the β1-adrenergic receptor blocker metoprolol . It is formed by metabolism of metoprolol by the cytochrome P450 (CYP) isoform CYP2D6 in vivo.

Chemical Properties

Off-White Solid

Uses

O-Desmethyl Metoprolol (Metoprolol EP Impurity H) is a metabolite of Metoprolol.

O-Desmethyl Metoprolol Preparation Products And Raw materials

Raw materials

Preparation Products

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O-Desmethyl Metoprolol Suppliers

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62572-94-5, O-Desmethyl MetoprololRelated Search:

3-[2-Hydroxy-3-[4-(2-methoxyethyl)phenoxy]propoxy]-1-isopropylamino-2-propanol 1-(2-methoxyethyl)-4-nitrobenzene 3-(ISOPROPYLAMINO)-1,2-PROPANEDIOL H 128/80 rac 1-Chloro-3-[4-(2-methoxyethyl)phenoxy]-2-propanol 1,3-Bis[(1-Methylethyl)aMino]-2-propanol Dihydrochloride 1-(isopropylamino)-3-phenoxy-2-propanol 3-[4-(2-Methoxyethyl)phenoxy]- 2-Propanol, 1-[2-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]- p-(2-Methoxyethyl) phenol 1,1′-[(1-Methylethyl)imino]bis[3-[4-(2-methoxyethyl)phenoxy]-2-propanol hydrochloride C-Desmethyl Metoprolol 4-Hydroxyphenethyl alcohol Metoprolol Impurity 1 Metoprolol EP IMpurity M 1-[4-(2-Methoxyethenyl)phenoxy]-3-[(1-Methylethyl)aMino]-2-propanol 1,1[(1-Methylethyl)imino]bis[3-[4-(2-methoxyethyl)phenoxy]-2-propanol (Mixture of diastereomers) LEVOBETAXOLOL

  • (-4-[2-Hydroxy-3-(isopropylamino)propoxy]phenylethyl Alcohol
  • (-O-Demethylmetoprolol
  • 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzeneethanol
  • H 105/22
  • O-Desmethyl Metoprolol
  • SL 80-008
  • O-demethylmetoprolo
  • Imp. H (EP):(2RS)-1-[4-(2-Hydroxyethyl)-phenoxy]-3-[(1-methylethyl)amino]propan-2-ol
  • Metoprolol-EP-Imp-H
  • Metoprolol EP Impurity H (Betaxolol EP Impurity B)
  • 1-(4-(2-hydroxyethyl)phenoxy)
  • Metoprolol-8
  • Metoprolol impurity 6/Metoprolol EP Impurity H/O-Desmethyl Metoprolol/1-(4-(2-hydroxyethyl)phenoxy)-3-(isopropylamino)propan-2-ol
  • Metoprolol Impurity 8
  • Betaxolol Impurity 1
  • SL 80-0088
  • Metoprolol Tartrate EP IMpurity-H
  • Metoprolol EP IMpurity H
  • 1-(4-(2-hydroxyethyl)phenoxy)-3-(isopropylamino)propan-2-ol
  • (2RS)-1-[4-(2-Hydroxyethyl)phenoxy]-3-[(1-methylethyl)amino]propan-2-ol
  • Betaxolol-001
  • Betaxolol EP Impurity B
  • Betaxolol Impurity 2(Betaxolol EP Impurity B)
  • Metoprolol Impurity 8(Metoprolol EP Impurity H)
  • (2RS)-1-[4-(2-Hydroxyethyl)phenoxy]
  • Benzeneethanol, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-
  • 13/5000 Metoprolol tartrate impurity H
  • Metoprolol EP Impurity H (O-Desmethyl Metoprolol)
  • Betaxolol Impurity B
  • Metoprolol Succinate Impurity H
  • Metoprolol Tartrate Impurity H
  • Metoprolol Succinate EP Impurity H
  • Betaxolol Hydrochloride Impurity B
  • Betaxolol Hydrochloride EP Impurity B
  • Metoprolol EP Impurity 8
  • Betaxolol EP Impurity B (Metoprolol EP Impurity H)
  • 62572-94-5
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals