ChemicalBook > CAS DataBase List > 9(R)-HODE

9(R)-HODE

Product Name
9(R)-HODE
CAS No.
10075-11-3
Chemical Name
9(R)-HODE
Synonyms
9(R)-HODE;9(R) HODE,9(R)HODE;NPDSHTNEKLQQIJ-WXUVIADPSA-N;9R-HYDROXY-10E,12Z-OCTADECADIENOIC ACID;10,12-Octadecadienoic acid, 9-hydroxy-, (9R,10E,12Z)-
CBNumber
CB4118460
Molecular Formula
C18H32O3
Formula Weight
296.44
MOL File
10075-11-3.mol
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9(R)-HODE Property

Boiling point:
416.1±33.0 °C(Predicted)
Density 
0.970±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
pka
4.78±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
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N-Bromosuccinimide Price

Cayman Chemical
Product number
38405
Product name
9(R)-HODE
Purity
≥98%
Packaging
25μg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
38405
Product name
9(R)-HODE
Purity
≥98%
Packaging
50μg
Price
$152
Updated
2024/03/01
Cayman Chemical
Product number
38405
Product name
9(R)-HODE
Purity
≥98%
Packaging
100μg
Price
$254
Updated
2024/03/01
Cayman Chemical
Product number
38405
Product name
9(R)-HODE
Purity
≥98%
Packaging
250μg
Price
$593
Updated
2024/03/01
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9(R)-HODE Chemical Properties,Usage,Production

Uses

9(R)-HODE is a monohydroxy fatty acid and metabolite of linoleic acid. It is formed from linoleic acid by COX and lipoxygenase (LO).9(R)-HODE induces chemotaxis, increases the levels of chemokine (C-C motif) receptor 9 (CCR9) and chemokine (C-X-C motif) receptor 4 (CXCR4), and inhibits IL-6 release in primary human monocytes. It inhibits CD3α- and CD28-induced proliferation of isolated human peripheral blood lymphocytes when used at a concentration of 25 μg/mL.

Definition

ChEBI: 9(R)-HODE is a 9-HODE in which the 9-hydroxy group has R-stereochemistry. It is a conjugate acid of a 9(R)-HODE(1-). It is an enantiomer of a 9(S)-HODE.

References

[1] Camacho, et al. Interleukin-1 enhances the ability of cultured human umbilical vein endothelial cells to oxidize linoleic acid. J. Biol. Chem. 270(29), 17279-17286 (1995).

9(R)-HODE Preparation Products And Raw materials

Raw materials

Preparation Products

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10075-11-3, 9(R)-HODERelated Search:


  • 9(R)-HODE
  • 9R-HYDROXY-10E,12Z-OCTADECADIENOIC ACID
  • NPDSHTNEKLQQIJ-WXUVIADPSA-N
  • 10,12-Octadecadienoic acid, 9-hydroxy-, (9R,10E,12Z)-
  • 9(R) HODE,9(R)HODE
  • 10075-11-3