ASP-ASP-CYS-GLY-LYS-LEU-PHE-SER-GLY-CYS-ASP-THR-ASN-ALA-ASP-CYS-CYS-GLU-GLY-TYR-VAL-CYS-ARG-LEU-TRP-CYS-LYS-LEU-ASP-TRP

Product Name: ASP-ASP-CYS-GLY-LYS-LEU-PHE-SER-GLY-CYS-ASP-THR-ASN-ALA-ASP-CYS-CYS-GLU-GLY-TYR-VAL-CYS-ARG-LEU-TRP-CYS-LYS-LEU-ASP-TRP
CAS No.: 741730-12-1
Chemical Name: ASP-ASP-CYS-GLY-LYS-LEU-PHE-SER-GLY-CYS-ASP-THR-ASN-ALA-ASP-CYS-CYS-GLU-GLY-TYR-VAL-CYS-ARG-LEU-TRP-CYS-LYS-LEU-ASP-TRP
Synonyms: HETEROPODATOXIN-2;ASP-ASP-CYS-GLY-LYS-LEU-PHE-SER-GLY-CYS-ASP-THR-ASN-ALA-ASP-CYS-CYS-GLU-GLY-TYR-VAL-CYS-ARG-LEU-TRP-CYS-LYS-LEU-ASP-TRP;L-Tryptophanamide, L-α-aspartyl-L-α-aspartyl-L-cysteinylglycyl-L-lysyl-L-leucyl-L-phenylalanyl-L-serylglycyl-L-cysteinyl-L-α-aspartyl-L-threonyl-L-asparaginyl-L-alanyl-L-α-aspartyl-L-cysteinyl-L-cysteinyl-L-α-glutamylglycyl-L-tyrosyl-L-valyl-L-cysteinyl-L-arginyl-L-leucyl-L-tryptophyl-L-cysteinyl-L-lysyl-L-leucyl-L-α-aspartyl-, cyclic (3→17),(10→22),(16→26)-tris(disulfide)
CBNumber: CB4118475
Molecular Formula: C144H207N39O46S6
Formula Weight: 3412.82
MOL File: Mol file

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ASP-ASP-CYS-GLY-LYS-LEU-PHE-SER-GLY-CYS-ASP-THR-ASN-ALA-ASP-CYS-CYS-GLU-GLY-TYR-VAL-CYS-ARG-LEU-TRP-CYS-LYS-LEU-ASP-TRP Property

Density: 1.588±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp.: −20°C
form: lyophilized powder
Sequence: Asp-Asp-Cys-Gly-Lys-Leu-Phe-Ser-Gly-Cys-Asp-Thr-Asn-Ala-Asp-Cys-Cys-Glu-Gly-Tyr-Val-Cys-Arg-Leu-Trp-Cys-Lys-Leu-Asp-Trp-NH2 (Disulfide bridge:Cys3-Cys17;Cys10-Cys22;Cys16-Cys26)

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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ASP-ASP-CYS-GLY-LYS-LEU-PHE-SER-GLY-CYS-ASP-THR-ASN-ALA-ASP-CYS-CYS-GLU-GLY-TYR-VAL-CYS-ARG-LEU-TRP-CYS-LYS-LEU-ASP-TRP Chemical Properties,Usage,Production

Uses

Heteropodatoxin-2, a peptides of 30-amino acid, is a heteropodatoxin. Heteropodatoxin-2 blocks Kv4.2 current expressed in Xenopus laevis oocytes in a voltage-dependent manner, with less block at more positive potentials[1].

References

[1] M C Sanguinetti, et al. Heteropodatoxins: peptides isolated from spider venom that block Kv4.2 potassium channels. Mol Pharmacol. 1997 Mar;51(3):491-8. PMID:9058605

ASP-ASP-CYS-GLY-LYS-LEU-PHE-SER-GLY-CYS-ASP-THR-ASN-ALA-ASP-CYS-CYS-GLU-GLY-TYR-VAL-CYS-ARG-LEU-TRP-CYS-LYS-LEU-ASP-TRP Preparation Products And Raw materials

Raw materials

Preparation Products

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ASP-ASP-CYS-GLY-LYS-LEU-PHE-SER-GLY-CYS-ASP-THR-ASN-ALA-ASP-CYS-CYS-GLU-GLY-TYR-VAL-CYS-ARG-LEU-TRP-CYS-LYS-LEU-ASP-TRP Suppliers

China 3 Switzerland 1 United States 1 Global 5

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Email: Eric@peptidego.com
Country: China
ProdList: 7408
Advantage: 58

Hangzhou Sinoda Pharmaceutical Technology Co. LTD

Tel: 0571-87213919 17306812703
Email: 3007955328@qq.com
Country: China
ProdList: 6979
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Alomone Labs

Tel: 4008-168-068 13121892008
Email: info@alomone.com
Country: China
ProdList: 1241
Advantage: 58

741730-12-1, ASP-ASP-CYS-GLY-LYS-LEU-PHE-SER-GLY-CYS-ASP-THR-ASN-ALA-ASP-CYS-CYS-GLU-GLY-TYR-VAL-CYS-ARG-LEU-TRP-CYS-LYS-LEU-ASP-TRPRelated Search:

HETEROPODATOXIN-2

ASP-ASP-CYS-GLY-LYS-LEU-PHE-SER-GLY-CYS-ASP-THR-ASN-ALA-ASP-CYS-CYS-GLU-GLY-TYR-VAL-CYS-ARG-LEU-TRP-CYS-LYS-LEU-ASP-TRP

L-Tryptophanamide, L-α-aspartyl-L-α-aspartyl-L-cysteinylglycyl-L-lysyl-L-leucyl-L-phenylalanyl-L-serylglycyl-L-cysteinyl-L-α-aspartyl-L-threonyl-L-asparaginyl-L-alanyl-L-α-aspartyl-L-cysteinyl-L-cysteinyl-L-α-glutamylglycyl-L-tyrosyl-L-valyl-L-cysteinyl-L-arginyl-L-leucyl-L-tryptophyl-L-cysteinyl-L-lysyl-L-leucyl-L-α-aspartyl-, cyclic (3→17),(10→22),(16→26)-tris(disulfide)

741730-12-1

Monovalent Ion Channels

Potassium Channel Modulators

Voltage-gated Ion Channels