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AMBENONIUM
- Product Name
- AMBENONIUM
- CAS No.
- 7648-98-8
- Chemical Name
- AMBENONIUM
- Synonyms
- Win-8077;AMBENONIUM;[Oxalylbis(iminoethylene)]bis[(2-chlorobenzyl)diethylaminium];N,N'-[(1,2-Dioxo-1,2-ethanediyl)bis(imino-2,1-ethanediyl)]bis[2-chloro-N,N-diethylbenzenemethanaminium];(2-chlorophenyl)methyl-[2-[[2-[(2-chlorophenyl)methyl-diethyl-ammonio]ethylcarbamoylformyl]amino]ethyl]-diethyl-azanium;(2-chlorophenyl)methyl-[2-[[2-[2-[(2-chlorophenyl)methyl-diethylazaniumyl]ethylamino]-2-oxoacetyl]amino]ethyl]-diethylazanium
- CBNumber
- CB41229499
- Molecular Formula
- C28H42Cl2N4O2+2
- Formula Weight
- 537.57
- MOL File
- 7648-98-8.mol
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AMBENONIUM Chemical Properties,Usage,Production
Definition
ChEBI: A symmetrical oxalamide-based bis-quaternary ammonium ion having ethyl and 2-chlorobenzyl groups attached to the nitrogens.
brand name
Mytelase (Sanofi Aventis).
Pharmacology
The pharmacological properties of ambenonium are similar to neostigmine and pyridostigmine, and it works by reversible inactivation of cholinesterase.
Synthesis
Ambenonium, [oxalyl-bis-(iminoethylen)]-bis-[ortho-(chlorobenzyl) diethylammonium] chloride (13.2.15), is made by reacting diethyloxalate with two moles of N,N-diethylethylendiamine, forming oxalyl-bis-(iminoethylen)-bis-N,N-diethylamine (13.2.14), which is alkylated by two moles of 2-chlorobenzylchloride, giving ambenonium (13.2.15) [46¨C48].
AMBENONIUM Preparation Products And Raw materials
Raw materials
Preparation Products
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