(4R)-4-[(3S,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid

Product Name: (4R)-4-[(3S,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
CAS No.: 1534-35-6
Chemical Name: (4R)-4-[(3S,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
Synonyms: isoLCA;solithocholic acid;5β-CHOLANIC ACID-3β-OL;Isolithocholic acid (ILCA);(3,5)-3-Hydroxycholan-24-oic acid;Isolithocholic Acid, 10 mM in DMSO;(3β,5β)-3-Hydroxycholan-24-oic acid;Isolithocholic acid (β-Lithocholic acid);Cholan-24-oic acid, 3-hydroxy-, (3β,5β)-;(3beta,5beta)-3-Hydroxycholan-24-oic Acid
CBNumber: CB41236037
Molecular Formula: C24H40O3
Formula Weight: 376.57
MOL File: 1534-35-6.mol

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(4R)-4-[(3S,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid Property

Melting point:: 90-95 °C
Boiling point:: 511.0±23.0 °C(Predicted)
Density: 1.073±0.06 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form: Solid
pka: 4.76±0.10(Predicted)
color: White to Off-White
InChIKey: SMEROWZSTRWXGI-WFVDQZAMSA-N
SMILES: [H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)[C@]3([H])CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC(O)=O

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Safety

WGK Germany: WGK 3
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29545
Product name: Isolithocholic Acid
Packaging: 5mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 29545
Product name: Isolithocholic Acid
Packaging: 25mg
Price: $298
Updated: 2024/03/01

Cayman Chemical

Product number: 29545
Product name: Isolithocholic Acid
Packaging: 10mg
Price: $129
Updated: 2024/03/01

TRC

Product number: H824865
Product name: (3β,5β)-3-Hydroxycholan-24-oicacid
Packaging: 250mg
Price: $1695
Updated: 2021/12/16

AK Scientific

Product number: 1227CB
Product name: Isolithocholicacid
Packaging: 5mg
Price: $187
Updated: 2021/12/16

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(4R)-4-[(3S,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid Chemical Properties,Usage,Production

Uses

(3β,5β)-3-Hydroxycholan-24-oic acid has been used for the study of the activation of β1 subunit-containing BK channels with respect to the structure of monohydroxylated bile acids.

Definition

ChEBI: A monohydroxy-5beta-cholanic acid with a beta-hydroxy substituent at position 3. The 3beta-hydroxy epimer of lithocholic acid.

in vivo

The levels of fecal Isolithocholic acid shows obvious decreases from day 28 onward in the high fat diet (HFD) group compared with rats fed a normal diet^[4].

IC 50

Microbial Metabolite

(4R)-4-[(3S,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(4R)-4-[(3S,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid Suppliers

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1534-35-6, (4R)-4-[(3S,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acidRelated Search:

(4R)-4-[(3S,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid

Isolithocholic acid (ILCA)

(R)-4-((3S,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

(3beta,5beta)-3-Hydroxycholan-24-oic Acid

isoLCA

(3β,5β)-3-Hydroxycholan-24-oic acid

Cholan-24-oic acid, 3-hydroxy-, (3β,5β)-

Isolithocholic acid (β-Lithocholic acid)

5β-CHOLANIC ACID-3β-OL

solithocholic acid

Isolithocholic Acid, 10 mM in DMSO

(R)-4-((3S,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid - [AC77900]

(3,5)-3-Hydroxycholan-24-oic acid

1534-35-6