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2-Chloro-9-methyl-9H-purin-6-amine

Product Name
2-Chloro-9-methyl-9H-purin-6-amine
CAS No.
7013-21-0
Chemical Name
2-Chloro-9-methyl-9H-purin-6-amine
Synonyms
2-Chloro-9-methyladenine;2-Chloro-6-amino-9-methylpurine;6-Amino-2-chloro-9-methylpurine;2-Chloro-9-methyl-9H-purin-6-amine;9H-Purin-6-amine, 2-chloro-9-methyl-
CBNumber
CB41241080
Molecular Formula
C6H6ClN5
Formula Weight
183.6
MOL File
7013-21-0.mol
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2-Chloro-9-methyl-9H-purin-6-amine Property

Boiling point:
360.9±52.0 °C(Predicted)
Density 
1.79±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
1.98±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C994120
Product name
2-Chloro-9-methyl-9H-purin-6-amine
Packaging
10mg
Price
$45
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0363655
Product name
2-CHLORO-9-METHYL-9H-PURIN-6-AMINE
Purity
95.00%
Packaging
5G
Price
$142.8
Updated
2021/12/16
AK Scientific
Product number
0319CB
Product name
2-Chloro-9-methyl-9H-purin-6-amine
Packaging
5g
Price
$1357
Updated
2021/12/16
Ambeed
Product number
A205750
Product name
2-Chloro-9-methyl-9H-purin-6-amine
Purity
95%
Packaging
100mg
Price
$79
Updated
2021/12/16
Ambeed
Product number
A205750
Product name
2-Chloro-9-methyl-9H-purin-6-amine
Purity
95%
Packaging
250mg
Price
$115
Updated
2021/12/16
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2-Chloro-9-methyl-9H-purin-6-amine Chemical Properties,Usage,Production

Synthesis

2382-10-7

7013-21-0

2,6-Dichloro-9-methyl-9H-purine (26) (1.01 g, 4.97 mmol) was used as a raw material and mixed with 32% ammonium hydroxide solution (20.4 mL, 164 mmol) in acetonitrile (20 mL). The reaction mixture was stirred at 55 °C for 5.5 hours. Subsequently, 32% ammonium hydroxide solution (20.4 mL, 164 mmol) was added to the reaction system and stirring was continued at 55°C for 19.5 hours. After completion of the reaction, the mixture was evaporated to dryness. The crude product obtained was suspended in methanol and filtered to afford the target compound 2-chloro-9-methyl-9H-purin-6-amine (27) as a white solid (746 mg, 82% yield) with a melting point >300 °C. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3) δ 8.10 (s, 1H), 7.72 (s, 2H), 3.69 (s, 3H); 13C NMR (101 MHz, CDCl3) δ 156.6 (C), 152.8 (C), 150.8 (C), 141.9 (CH), 117.6 (C), 29.5 ( CH3) confirmed. The mass spectrum (ESI, 20 V) showed a m/z of 184.1 (MH+, 100).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 11, p. 3427 - 3433

2-Chloro-9-methyl-9H-purin-6-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-9-methyl-9H-purin-6-amine Suppliers

China 25 India 1 Switzerland 2 United Kingdom 1 United States 3 Global 32
Biosynth AG
Tel
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Fax
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Email
welcome@biosynth.ch
Country
Switzerland
ProdList
3324
Advantage
72
Achemica
Tel
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Fax
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Email
contact@achemica.com
Country
Switzerland
ProdList
6155
Advantage
50

7013-21-0, 2-Chloro-9-methyl-9H-purin-6-amineRelated Search:


  • 2-Chloro-9-methyl-9H-purin-6-amine
  • 6-Amino-2-chloro-9-methylpurine
  • 2-Chloro-6-amino-9-methylpurine
  • 2-Chloro-9-methyladenine
  • 9H-Purin-6-amine, 2-chloro-9-methyl-
  • 7013-21-0