NSC68992
- Product Name
- NSC68992
- CAS No.
- 934-26-9
- Chemical Name
- NSC68992
- Synonyms
- NSC68992;6-CHLORO-3-HYDRAZINYLPYRIDAZIN-4-AMINE;6-chloro-3-hydrazineylpyridazin-4-amine;4-Pyridazinamine, 6-chloro-3-hydrazinyl-
- CBNumber
- CB41251119
- Molecular Formula
- C4H6ClN5
- Formula Weight
- 159.58
- MOL File
- 934-26-9.mol
NSC68992 Property
- Melting point:
- 190 °C(Solv: ethanol (64-17-5))
- Boiling point:
- 304.9±45.0 °C(Predicted)
- Density
- 1.87±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- pka
- 4.96±0.40(Predicted)
N-Bromosuccinimide Price
- Product number
- C585623
- Product name
- 6-Chloro-3-hydrazinylpyridazin-4-amine
- Packaging
- 50mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- Z5361
- Product name
- 6-Chloro-3-hydrazinylpyridazin-4-amine
- Packaging
- 100mg
- Price
- $166
- Updated
- 2021/12/16
- Product number
- FC141591
- Product name
- 6-Chloro-3-hydrazinylpyridazin-4-amine
- Packaging
- 250mg
- Price
- $187.5
- Updated
- 2021/12/16
- Product number
- FC141591
- Product name
- 6-Chloro-3-hydrazinylpyridazin-4-amine
- Packaging
- 50mg
- Price
- $54
- Updated
- 2021/12/16
- Product number
- FC141591
- Product name
- 6-Chloro-3-hydrazinylpyridazin-4-amine
- Packaging
- 100mg
- Price
- $94
- Updated
- 2021/12/16
NSC68992 Chemical Properties,Usage,Production
Uses
6-Chloro-3-hydrazinylpyridazin-4-amine is used to synthesize heterocyclic ring system as potential purine antagonist.
Synthesis
823-58-5
934-26-9
Step 112.2: Synthesis of 6-chloro-3-hydrazinopyridazin-4-amine To a stirred suspension of 3,6-dichloropyridazin-4-amine (1.49 g, 9.09 mmol) in ethanol (15 mL) was slowly added hydrazine hydrate (11.04 mL, 227 mmol). The reaction mixture was heated to 100 °C and stirred for 3 hours. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently concentrated under reduced pressure to remove the solvent. The crude product was ground with deionized water (25 mL) to afford the title compound 6-chloro-3-hydrazinopyridazin-4-amine (478 mg, 3 mmol, 33% yield) as a yellow solid. Analytical data: Retention time (t R): 0.24 min (LC-MS method 2);. Positive ion mode electrospray ionization mass spectrometry (ESI-MS): m/z 160 [M + H]+; Negative ion mode electrospray ionization mass spectrometry (ESI-MS): m/z 158 [M-H]-.
References
[1] Journal of Medicinal Chemistry, 2014, vol. 57, # 6, p. 2807 - 2812
[2] Patent: US2014/349990, 2014, A1. Location in patent: Paragraph 1053; 1054
[3] Patent: WO2014/191896, 2014, A1. Location in patent: Page/Page column 218
[4] Patent: US4728355, 1988, A
NSC68992 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from NSC68992 manufacturers
- Product
- 6-Chloro-3-hydrazinylpyridazin-4-amine 934-26-9
- Price
- US $0.00/KG
- Min. Order
- 1g
- Purity
- 97%minHPLC
- Supply Ability
- 5kgs/month
- Release date
- 2021-11-15