ChemicalBook > CAS DataBase List > AC-NLE-PRO-NLE-ASP-AMC

AC-NLE-PRO-NLE-ASP-AMC

Product Name
AC-NLE-PRO-NLE-ASP-AMC
CAS No.
355140-49-7
Chemical Name
AC-NLE-PRO-NLE-ASP-AMC
Synonyms
AC-NLE-PRO-NLE-ASP-MCA;AC-NLE-PRO-NLE-ASP-AMC;N-Acetyl-L-norleucyl-L-prolyl-L-norleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine;L-α-Asparagine, N-acetyl-L-norleucyl-L-prolyl-L-norleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;(S)-3-((S)-2-((S)-1-((S)-2-Acetamidohexanoyl)pyrrolidine-2-carboxamido)hexanamido)-4-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-4-oxobutanoic acid
CBNumber
CB4128342
Molecular Formula
C33H45N5O9
Formula Weight
655.74
MOL File
Mol file
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AC-NLE-PRO-NLE-ASP-AMC Property

Boiling point:
1028.3±65.0 °C(Predicted)
Density 
1.278±0.06 g/cm3(Predicted)
storage temp. 
-15°C
pka
4.10±0.10(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21639
Product name
Ac-Nle-Pro-Nle-Asp-AMC
Purity
≥98%
Packaging
1mg
Price
$143
Updated
2021/12/16
Cayman Chemical
Product number
21639
Product name
Ac-Nle-Pro-Nle-Asp-AMC
Purity
≥98%
Packaging
500μg
Price
$75
Updated
2021/12/16
Cayman Chemical
Product number
21639
Product name
Ac-Nle-Pro-Nle-Asp-AMC
Purity
≥98%
Packaging
5mg
Price
$525
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA110588
Product name
Ac-Nle-Pro-Nle-Asp-AMC
Packaging
5mg
Price
$591
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA110588
Product name
Ac-Nle-Pro-Nle-Asp-AMC
Packaging
10mg
Price
$1027.8
Updated
2021/12/16
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AC-NLE-PRO-NLE-ASP-AMC Chemical Properties,Usage,Production

Uses

Ac-Nle-Pro-Nle-Asp-AMC is a specific substrate for 26S proteasome. Ac-Nle-Pro-Nle-Asp-AMC can be used for the 26S proteasome caspase-like activity analysis[1][2][3].

References

[1] Dunlop RA, et al. The impact of specific oxidized amino acids on protein turnover in J774 cells. Biochem J. 2008 Feb 15;410(1):131-40. DOI:10.1042/BJ20070161
[2] Kirk-Ballard H, et al. An extract of Artemisia dracunculus L. inhibits ubiquitin-proteasome activity and preserves skeletal muscle mass in a murine model of diabetes. PLoS One. 2013;8(2):e57112. DOI:10.1371/journal.pone.0057112
[3] Pakavathkumar P, et al. Methylene Blue Inhibits Caspases by Oxidation of the Catalytic Cysteine. Sci Rep. 2015 Sep 24;5:13730. DOI:10.1038/srep13730

AC-NLE-PRO-NLE-ASP-AMC Preparation Products And Raw materials

Raw materials

Preparation Products

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AC-NLE-PRO-NLE-ASP-AMC Suppliers

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355140-49-7, AC-NLE-PRO-NLE-ASP-AMCRelated Search:


  • AC-NLE-PRO-NLE-ASP-AMC
  • AC-NLE-PRO-NLE-ASP-MCA
  • L-α-Asparagine, N-acetyl-L-norleucyl-L-prolyl-L-norleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
  • N-Acetyl-L-norleucyl-L-prolyl-L-norleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine
  • (S)-3-((S)-2-((S)-1-((S)-2-Acetamidohexanoyl)pyrrolidine-2-carboxamido)hexanamido)-4-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-4-oxobutanoic acid
  • 355140-49-7