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7-Benzothiazolecarboxylicacid,2-amino-(6CI,9CI)

Product Name
7-Benzothiazolecarboxylicacid,2-amino-(6CI,9CI)
CAS No.
71224-95-8
Chemical Name
7-Benzothiazolecarboxylicacid,2-amino-(6CI,9CI)
Synonyms
2-Aminobenzothiazole-7-carboxylic acid;2-amino-7-Benzothiazolecarboxylic acid;7-Benzothiazolecarboxylic acid, 2-amino-;2-Aminobenzo[d]thiazole-7-carboxylic acid;2-aMino-1,3-benzothiazole-7-carboxylic acid;7-Benzothiazolecarboxylicacid,2-amino-(6CI,9CI)
CBNumber
CB41284083
Molecular Formula
C8H6N2O2S
Formula Weight
194.21
MOL File
71224-95-8.mol
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7-Benzothiazolecarboxylicacid,2-amino-(6CI,9CI) Property

Boiling point:
466.6±37.0 °C(Predicted)
Density 
1.604
storage temp. 
Sealed in dry,Room Temperature
pka
1.09±0.10(Predicted)
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Safety

HS Code 
2934208090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A638625
Product name
2-Aminobenzo[D]thiazole-7-carboxylicAcid
Packaging
50mg
Price
$90
Updated
2021/12/16
TRC
Product number
A638625
Product name
2-Aminobenzo[D]thiazole-7-carboxylicAcid
Packaging
100mg
Price
$130
Updated
2021/12/16
TRC
Product number
A638625
Product name
2-Aminobenzo[D]thiazole-7-carboxylicAcid
Packaging
10mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA142142
Product name
2-Aminobenzo[d]thiazole-7-carboxylic acid
Packaging
100mg
Price
$76
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA142142
Product name
2-Aminobenzo[d]thiazole-7-carboxylic acid
Packaging
500mg
Price
$260
Updated
2021/12/16
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7-Benzothiazolecarboxylicacid,2-amino-(6CI,9CI) Chemical Properties,Usage,Production

Synthesis

37182-75-5

71224-95-8

General procedure for the synthesis of 2-aminobenzothiazole-7-carboxylic acid from 1-(3-carboxyphenyl)-2-thiourea: 3-isothiocyanatobenzoic acid (1.0 g, 5.6 mmol) was dissolved in 40 mL of ethanol and stirred for 1 h at room temperature while ammonia was passed into the solution. The resulting white precipitate was separated by filtration. The filtrate was concentrated to induce more white solid precipitate, which was again separated by filtration.The total yield of 3-thiodibenzoic acid was 1.06 g (97%). 3-Thiobisbenzoic acid (1.06 g, 5.41 mmol) was suspended in 25 mL of chloroform at room temperature and a solution of bromine (0.4 mL, 8.0 mmol) was added slowly and dropwise. The reaction mixture was heated to reflux for 3 hours followed by stirring at room temperature for 60 hours. The solvent was removed by evaporation and after addition of water, the resulting solid was separated by filtration. The crude product was washed with water and dried to give 1.03 g (98%) of 2-aminobenzothiazole-7-carboxylic acid as a gray solid.

References

[1] Patent: WO2004/11460, 2004, A2. Location in patent: Page 59

7-Benzothiazolecarboxylicacid,2-amino-(6CI,9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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7-Benzothiazolecarboxylicacid,2-amino-(6CI,9CI) Suppliers

JinYan Chemicals(ShangHai) Co.,Ltd.
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Nantong Bosu Pharmaceutical Technology Co., Ltd.
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View Lastest Price from 7-Benzothiazolecarboxylicacid,2-amino-(6CI,9CI) manufacturers

Career Henan Chemical Co
Product
7-Benzothiazolecarboxylicacid,2-amino-(6CI,9CI) 71224-95-8
Price
US $1.00/g
Min. Order
1g
Purity
99.0%
Supply Ability
100 kg
Release date
2020-01-10

71224-95-8, 7-Benzothiazolecarboxylicacid,2-amino-(6CI,9CI)Related Search:


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