ChemicalBook > CAS DataBase List > 2'-deoxy-4'-thiocytidine
2'-deoxy-4'-thiocytidine
- Product Name
- 2'-deoxy-4'-thiocytidine
- CAS No.
- 134111-30-1
- Chemical Name
- 2'-deoxy-4'-thiocytidine
- Synonyms
- 4′-thio-2-deoxycytidine;4’-thio-2’-deoxycytidine;2'-deoxy-4'-thiocytidine;Cytidine, 2'-deoxy-4'-thio-
- CBNumber
- CB41312986
- Molecular Formula
- C9H13N3O3S
- Formula Weight
- 243.28
- MOL File
- 134111-30-1.mol
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2'-deoxy-4'-thiocytidine Chemical Properties,Usage,Production
Uses
2′-Deoxy-4′-thiocytidine (T-dCyd) is a novel epigenetic agent. 2′-Deoxy-4′-thiocytidine administrations led to a significant p21 increase. 2′-Deoxy-4′-thiocytidine can eradicate of tumor cells in the double-mutant xenografts[1].
References
[1] Sherry X Yang, et al. TET2 and DNMT3A mutations and exceptional response to 4'-thio-2'-deoxycytidine in human solid tumor models. J Hematol Oncol. 2021, 14, 1. DOI:10.1186/s13045-021-01091-5
2'-deoxy-4'-thiocytidine Preparation Products And Raw materials
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Preparation Products
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