ChemicalBook > CAS DataBase List > ACETYLCHOLINE IODIDE

ACETYLCHOLINE IODIDE

Product Name: ACETYLCHOLINE IODIDE
CAS No.: 2260-50-6
Chemical Name: ACETYLCHOLINE IODIDE
Synonyms: ACH;CEK2;JTK4;CD333;HSFGFR3EX;acetylcolina;CD333 antigen;acetyl-choliniodide;Acetylholine iodide;Acetycholine iodide
CBNumber: CB4131593
Molecular Formula: C7H16INO2
Formula Weight: 273.11
MOL File: 2260-50-6.mol

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ACETYLCHOLINE IODIDE Property

Melting point:: 161-164 °C
Density: 1.4816 (estimate)
storage temp.: -20°C
solubility: Soluble in DMSO
form: Crystalline Powder
color: White
biological source: rabbit
Water Solubility: almost transparency
Sensitive: Light Sensitive & Hygroscopic
BRN: 3571339
Specific Activity: 95-129nmol/min·mg
CAS DataBase Reference: 2260-50-6(CAS DataBase Reference)
EPA Substance Registry System: Ethanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, iodide (2260-50-6)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: KH3300000
F: 8-9
TSCA: Yes
HS Code: 29239000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SRP5301
Product name: FGFR3 (K650E), active, GST tagged human
Purity: PRECISIO<SUP>®</SUP>, recombinant, expressed in baculovirus infected <I>Sf</I>9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Packaging: 10 μg
Price: $401
Updated: 2025/07/31

Sigma-Aldrich

Product number: SAB4500888
Product name: Anti-FGFR3 antibody produced in rabbit
Purity: affinity isolated antibody
Packaging: 100 μg
Price: $522
Updated: 2025/07/31

Sigma-Aldrich

Product number: SAB3501041
Product name: Anti-FGFR3 antibody produced in rabbit
Purity: affinity isolated antibody
Packaging: 100μG
Price: $531
Updated: 2025/07/31

Sigma-Aldrich

Product number: F7930
Product name: FGFR3 (397-end), active, GST tagged human
Purity: PRECISIO? Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Packaging: 10μg
Price: $537
Updated: 2025/07/31

Sigma-Aldrich

Product number: A7000
Product name: Acetylcholine iodide
Purity: ≥97%
Packaging: 5g
Price: $63.5
Updated: 2025/07/31

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ACETYLCHOLINE IODIDE Chemical Properties,Usage,Production

Chemical Properties

WHITE CRYSTALLINE POWDER

Uses

Acetylcholine is an endogenous neurotransmitter at cholinergic synapses that amplifies action potential of the sarcolemma thereby inducing muscle contractions. Acetylcholine iodide is used as an acetylcholine receptor agonist to identify, characterize and differentiate among types of cholinergic receptors. Acetylcholine iodide is used as a substrate to identify and characterize natural and mutated acetylcholinesterase(s).

Biochem/physiol Actions

Endogenous neurotransmitter at cholinergic synapses; amplifies action potential of the sarcolemma thereby inducing muscle contractions.

Synthesis

1634-34-0

17773-10-3

2260-50-6

General procedure for the synthesis of 2-acetoxy-N,N,N-trimethylethane-1-ammonium iodide from 3,5-dihydroxy-4-acetyltoluene and (2-hydroxyethyl)trimethylammonium iodide: 3 moles of 3,5-dihydroxy-4-acetyltoluene and 5 moles of (2-hydroxyethyl)trimethylammonium iodide were added to a reaction vessel with controlled stirring at a speed of 130 rpm, and the temperature was raised to 65 °C. The temperature was increased to 65 °C. The temperature was maintained with continuous stirring until the reactants were completely dissolved. Subsequently, the reaction mixture was allowed to stand for 120 minutes. The temperature of the solution was lowered to 15 °C to promote crystal precipitation, followed by filtration. The crystals were washed with 85% cyclohexane solution, followed by washing again with 90% toluene solution. Finally, dehydration was carried out using anhydrous potassium carbonate as dehydrating agent to afford 761.67 g of 2-acetoxy-N,N,N-trimethylethane-1-ammonium iodide in 93% yield.

in vivo

Acetylcholine iodide (3 μg; i.v.) increases the electrical potential difference in the proximal colon of rats^[2].
Acetylcholine iodide (25 mg/kg; subcutaneous injection; twice a day; 15 days) induces mammary ductal growth in some virgin rats^[3].
Acetylcholine iodide (25 mg/kg; subcutaneous injection; twice a day; 5 days) induces lobular-acinar growth and secretion in the mammary glands of virgin rats pretreated with estrogen^[3].

Animal Model:	Female albino rats (Carworth, weighing 175 - 200 g, age unspecified) for studying mammary growth and lactation induction; Female albino rats (Carworth, postparturient, litter removed on 4th day after parturition) for studying maintenance of mammary structure and secretion^[3].
Dosage:	25 mg/kg, 50 mg/kg (dissolved in an unspecified solvent for subcutaneous injection)
Administration:	Subcutaneous injection, twice daily for 15 days (for induction in virgin rats), twice daily for 5 days after 10 days of estradiol pretreatment (for induction in estrogen-primed virgin rats), twice daily for 10 days (for maintenance in lactating rats after litter removal)
Result:	Induced duct growth in some cases without estradiol priming, and lobule-alveolar growth and secretion with estradiol priming in virgin rats. Retarded mammary involution and maintained lactation in lactating rats after litter removal.

IC 50

Human Endogenous Metabolite

References

[1] Patent: CN108250089, 2018, A. Location in patent: Paragraph 0011; 0013; 0015

ACETYLCHOLINE IODIDE Preparation Products And Raw materials

Raw materials

Choline Bitartrate Ethanol 2-Iodoethanol Barium hydroxide Trimethylamine Isopropyl alcohol ACETYL IODIDE

Preparation Products

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View Lastest Price from ACETYLCHOLINE IODIDE manufacturers

Career Henan Chemical Co

Product: ACETYLCHOLINE IODIDE 2260-50-6
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-13

2260-50-6, ACETYLCHOLINE IODIDERelated Search:

BUTYRYLCHOLINE IODIDE BENZOYLCHOLINE IODIDE ACETYLCHOLINE IODIDE ACETYL IODIDE Choline hydroxide CHOLINE PHOSPHONIUM IODIDE CHOLINE IODIDE O,O-SUCCINYLDICHOLINE IODIDE ACETYL-BETA-METHYLCHOLINE IODIDE PROPIONYLCHOLINE IODIDE (-)-BICUCULLINE METHIODIDE MYRISTOYL CHOLINE IODIDE Dicolinium iodide etipirium iodide STEAROYLCHOLINE IODIDE PALMITOYLCHOLINE IODIDE 6-BROMO-2-CARBONAPHTHOXYCHOLINE IODIDE

N-(2-HYDROXYETHYL)TRIMETHYLAMMONIUM IODIDE ACETATE

ACH

ACETYLCHOLINE IODIDE

2-(acetyloxy)-n,n,n-trimethyl-ethanamiuiodide

Acetylcholine iodide;(2-Acetoxyethyl)-trimethyammoniumiodide

ACETYLCHOLINE IODIDE CRYSTALLINE

O-AcetylcholineIodide

2-(ACETYLOXY)-N,N,N-TRIMETHYLETHANAMINIUM IODIDE

2-ACETOXYETHYLTRIMETHYLAMMONIUM IODIDE

Acetylcholine iodide,99%

2-(Dimethylamino)ethyl acetate methiodide

Acetylchloineiodide

2-acetoxy-N,N,N-triMethylethanaMiniuM iodide

Anti-FGFR3 (C-terminal) antibody produced in rabbit

2-acetyloxyethyl(trimethyl)azanium,iodide

2-(acetyloxy)-n,n,n-trimethylethanamiumiodide

acetyl-choliniodide

acetylcolina

Anti-FGFR3 antibody produced in rabbit

CEK2

FGFR3 (397-end), active, GST tagged human

HSFGFR3EX

JTK4

FGFR3 (K650E), active, GST tagged human

Acetylholine iodide

choline,iodide,acetate(ester)

cholineacetate(ester),iodide

(2-Hydroxyethyl)-trimethylammonium iodide acetate

Acetycholine iodide

(2-Acetoxyethyl)-trimethyammoniumiodide

AcetylcholineIodide&gt

ACETYLCHOLINE IODIDE FOR SYNTHESIS

Acetylcholine iodide, GR 99%

Acetylcholine Iodide extrapure, 99%

2-Acetoxy-N,N,N-trimethylethan-1-aminium iodide

Acetyl Choline Iodide 99% AR

Acetylcholine iodide, 10 mM in DMSO

CD333 antigen

CD333

2260-50-6

CH3CO2CH2CH2NCH33I

CH33NICH2CH2OCOCH3

C7H16INO2

C7H16NO2I

Quaternary Ammonium Compounds

Ammonium Iodides (Quaternary)

Phase Transfer Catalysts

Synthetic Reagents

Ammonium Salts

Substrates

Ammonium Iodides (Quaternary)

Quaternary Ammonium Compounds