marcfortine A

Product Name: marcfortine A
CAS No.: 75731-43-0
Chemical Name: marcfortine A
Synonyms: UK 111866;marcfortine A;Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,2'(3'H)-[1H,4H-3a,9a](iminomethano)cyclopenta[b]quinolizine]-9,11'(10H)-dione, 6',7',8',9',10',10'a-hexahydro-1',1',4,4,12'-pentamethyl-, (2'R,3'aS,9'aS,10'aS)-
CBNumber: CB41323193
Molecular Formula: C28H35N3O4
Formula Weight: 477.602
MOL File: 75731-43-0.mol

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marcfortine A Property

Melting point:: 245 °C
Boiling point:: 660.6±55.0 °C(Predicted)
Density: 1.33±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Methanol: soluble
form: A solid
pka: 12.05±0.60(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 23486
Product name: Marcfortine A
Purity: ≥99%
Packaging: 1mg
Price: $340
Updated: 2024/03/01

Cayman Chemical

Product number: 23486
Product name: Marcfortine A
Purity: ≥99%
Packaging: 5mg
Price: $1523
Updated: 2024/03/01

Usbiological

Product number: M2374-75
Product name: Marcfortine A
Packaging: 1mg
Price: $588
Updated: 2021/12/16

TRC

Product number: M197305
Product name: MarcfortineA
Packaging: 2.5mg
Price: $625
Updated: 2021/12/16

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marcfortine A Chemical Properties,Usage,Production

Description

Marcfortine A is an indole alkaloid originally isolated from P. roqueforti. It has nematocidal activity against the parasitic nematode H. contortus (LD₉₉ = 0.06 μg/ml) and inhibits motility of adult worms (EC₅₀ = 2 μM)., Marcfortine A eliminates H. contortus, T. colubriformis, and O. ostertagi from experimentally infected jirds (ED₉₅s = 0.33, 0.11, and 2.5 mg/animal, respectively). It dose-dependently inhibits nicotine-induced calcium mobilization in SH-SY5Y and TE-671 cells expressing α₃ subunit-containing human nicotinic acetylcholine receptors (nAChRs) and muscle-type nAChRs, respectively.

Uses

Marcfortine A is an indole alkaloid, isolated from Aspergillus and Pencillium species, with potent nematocidal activity. The marcfortines are structurally related to paraherquamides and are thought to act by blocking cholinergic neuromuscular transmission.

Uses

Marcfortine A is an indole alkaloid isolated from Aspergillus and Pencillium species.

marcfortine A Preparation Products And Raw materials

Raw materials

Preparation Products

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marcfortine A Suppliers

China 12 United Kingdom 1 United States 5 Global 18

Shanghai EFE Biological Technology Co., Ltd.

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TargetMol Chemicals Inc.

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75731-43-0, marcfortine ARelated Search:

C-[1-(4-METHOXY-PHENYL)-CYCLOPENTYL]-METHYLAMINE N-CYCLOPENTYL-N-METHYL-2-PIPERIDINEMETHANAMINE 2H-Indol-2-one,1,3-dihydro-6,7-dihydroxy-(9CI) ALPHA-PROPYLDOPACETAMIDE 1,1-DIMETHYL-2-PIPERIDIN-1-YL-ETHYLAMINE CHEMBRDG-BB 4017497 CHEMBRDG-BB 4011370 [1-(3,4-DIMETHOXYPHENYL)CYCLOPENTYL]METHANAMINE CHEMBRDG-BB 4011371 2,5-Diazabicyclo[2.2.2]octane 2H-Pyrido[1,2-a]pyrazin-1(6H)-one,hexahydro-(6CI,8CI,9CI) (1S,4S)-2,5-DIAZABICYCLO(2.2.2)OCTANE marcfortine A

marcfortine A

UK 111866

Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,2'(3'H)-[1H,4H-3a,9a](iminomethano)cyclopenta[b]quinolizine]-9,11'(10H)-dione, 6',7',8',9',10',10'a-hexahydro-1',1',4,4,12'-pentamethyl-, (2'R,3'aS,9'aS,10'aS)-

75731-43-0