Etimizol

Product Name: Etimizol
CAS No.: 64-99-3
Chemical Name: Etimizol
Synonyms: Etimizol;Etimizole;Ethymizol;Antiffine;Ethymisol;Ethimizole;Ethymisole;Etimizol, 99.5%;Ethylnorantifein;Ethylnorantifeine
CBNumber: CB41343533
Molecular Formula: C9H14N4O2
Formula Weight: 210.23
MOL File: 64-99-3.mol

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Etimizol Property

Melting point:: 143-144℃
Boiling point:: 563.4±35.0 °C(Predicted)
Density: 1.26±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Ethanol: ≥ 33.33 mg/mL (158.54 mM)
form: Solid
pka: 14.22±0.46(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FE65019
Product name: Etimizol
Packaging: 50mg
Price: $70
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FE65019
Product name: Etimizol
Packaging: 100mg
Price: $125
Updated: 2021/12/16

AK Scientific

Product number: 3660AH
Product name: Etimizol
Packaging: 50mg
Price: $144
Updated: 2021/12/16

AK Scientific

Product number: 3660AH
Product name: Etimizol
Packaging: 100mg
Price: $218
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FE65019
Product name: Etimizol
Packaging: 250mg
Price: $237.5
Updated: 2021/12/16

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Etimizol Chemical Properties,Usage,Production

Uses

Etimizol(Ethymisole; Antiffine; Ethylnorantifein) was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain). Etimizol can decrease the K-+ permeability of neurons' membrane during action potential.

in vivo

The time interval between administration ofetimizol (3 mg/kg) and the onset of learning varied between 0.5 and 3 h in the several series. Etimizol (Ethymisole) did not facilitate the learning in rats whatever the time of administration and biological modality of reinforcement [1]. After administration of Etimizol (Ethymisole) at doses of 10 or 1 mg/loop mean residence time of etimizol in the loop was 20.1 and 7.6 min, respectively, with mean standard deviation being 3.1 and 0.8, respectively [2]. Extracellular application of 5--10 mM/L Etimizol (Ethymisole) exerted a specific effect on the giant neurons of the Coretus corneus isolated nervous system: action potential duration increased significantly, speed of development of its descending phase decreased, as well as the trace hyperpolarization amplitude [3].

References

[1] Borisova GIu. Effect of etimizol on instrumental learning in rats. Biull Eksp Biol Med. 1985 Jun;99(6):705-6. PMID:4016262
[2] Trnovec T, et al. Etimizol absorption from the small intestine in dogs: the dependence on dosage. Biull Eksp Biol Med. 1986 Dec;102(12):729-30. PMID:3801627
[3] Vislobokov AI, et al. Elektrophysiological parameters of mollusk neurons under the influence of etimizol. Fiziol Zh SSSR Im I M Sechenova. 1975 Jun;61(6):917-24. PMID:1132537

Etimizol Preparation Products And Raw materials

Raw materials

Preparation Products

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Etimizol Suppliers

China 48 United Kingdom 2 United States 7 Global 57

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64-99-3, EtimizolRelated Search:

1,5-DIMETHYL-1H-IMIDAZOLE-4-CARBALDEHYDE 1H-IMIDAZOLE-4,5-DICARBOXYLIC ACID BIS-METHYLAMIDE Etimizol IMIDAZOLE-4,5-DICARBOXAMIDE Antiphein

Etimizol

Antiffine

Ethimizole

Ethymisol

Ethymisole

Ethymizol

Etimizole

Ethylnorantifein

Ethylnorantifeine

Ethylnorantiffeine

N,N'-Dimethyl-1-ethylimidazole-4,5-dicarboxamide

1-Ethyl-4-N,5-N-dimethyl-1H-imidazole-4,5-dicarboxamide

Etimizol(Ethymisole

ETIMIZOL(ETHYMISOLE; ANTIFFINE; ETHYLNORANTIFEIN)

ETHYMISOLE; ANTIFFINE; ETHIMIZOLE; ETHYLNORANTIFEIN; ETHYLNORANTIFEINE; ETHYLNORANTIFFEINE; ETHYMISOL; ETHYMISOLE; ETIMIZOLE

Etimizol, 99.5%

1H-Imidazole-4,5-dicarboxamide, 1-ethyl-N4,N5-dimethyl-

Inhibitor,Etimizol,inhibit

64-99-3