R(+)-1-(PENTAFLUOROPHENYL)ETHANOL Property

Melting point:

41-42 °C(lit.)

Boiling point:

162.9±0.0 °C(Predicted)

Density 

1.498±0.06 g/cm3(Predicted)

Flash point:

189 °F

pka

13.14±0.20(Predicted)

optical activity

[α]20/D +7.0±0.5°, c = 1% in pentane

BRN 

5268492

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

F 

10

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

R(+)-1-(PENTAFLUOROPHENYL)ETHANOL Chemical Properties,Usage,Production

Purification Methods

Recrystallise the ethanol from n-pentane at -40o and sublime it at 25o/0.3mm (use ice-cooled cold finger). It has also been purified by column chromatography through Kieselgel 60 (0.063-0.2mm mesh, Merck) and eluted with EtOAc/n-hexane (1:5), then recrystallised from n-pentane and sublimed in a vacuum. It has RF on Kieselgel 60 F254 TLC foil and eluting with EtOAc/n-hexane (1:5). [Meese Justus Liebigs Ann Chem 2004 1986.]