clomesone

Product Name: clomesone
CAS No.: 88343-72-0
Chemical Name: clomesone
Synonyms: SRI-6155;clomesone;NSC-338947;Chlorethyl SOSO;Clomesone, 10 mM in DMSO;2-Chloroethyl methanesulfonylmethanesulfonate;(Methylsulfonyl)methanesulfonic acid 2-chloroethyl ester;Methanesulfonic acid, 1-(methylsulfonyl)-, 2-chloroethyl ester
CBNumber: CB41352791
Molecular Formula: C4H9ClO5S2
Formula Weight: 236.695
MOL File: 88343-72-0.mol

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Hazard and Precautionary Statements (GHS)

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clomesone Chemical Properties,Usage,Production

Uses

Clomesone (NSC 338947) is a compound with antitumor activity. Clomesone induces the formation of cross-links between DNA strands in cell lines. Clomesone is inactive against most human colorectal cancer solid tumor cell lines in vitro, has no significant activity against mouse tumors in vivo, and is accompanied by bone marrow suppression. Its pharmacokinetic behavior indicates that it cannot reach effective concentrations at the tumor site.

References

[1] Pre-clinical evaluation of a novel chloroethylating agent, Clomesone DOI:10.1038/bjc.1993.85
[2] M E Dolan, et al. Effect of O6-methylguanine on DNA interstrand cross-link formation by chloroethylnitrosoureas and 2-chloroethyl(methylsulfonyl)methanesulfonate. Cancer Res. 1988 Jul 1;48(13):3603-6. PMID:2837318

clomesone Preparation Products And Raw materials

Raw materials

Preparation Products

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clomesone Suppliers

CHINA 8 United States 2 Global 10

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
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Shanghai Yifei Biotechnology Co. , Ltd.

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TargetMol Chemicals Inc.

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Sangon Biotech (Shanghai) Co.,Ltd.

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Biosynth Biological Technology (Suzhou) Co Ltd

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Wuxi Likang Biomedical Technology Co., Ltd

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TargetMol Chemicals Inc.

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Country: United States
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Guangzhou Taozhu Biotechnology Co., Ltd

Tel: 4008200310
Country: CHINA
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88343-72-0, clomesoneRelated Search:

2-CHLOROETHYL METHANESULFONATE clomesone

clomesone

(Methylsulfonyl)methanesulfonic acid 2-chloroethyl ester

Chlorethyl SOSO

NSC-338947

SRI-6155

Methanesulfonic acid, 1-(methylsulfonyl)-, 2-chloroethyl ester

2-Chloroethyl methanesulfonylmethanesulfonate

Clomesone, 10 mM in DMSO

88343-72-0

C4H9ClO5S2