ChemicalBook > CAS DataBase List > 1,1,1-trifluoro-4-(4-hydroxyphenyl)butan-2-one

1,1,1-trifluoro-4-(4-hydroxyphenyl)butan-2-one

Product Name
1,1,1-trifluoro-4-(4-hydroxyphenyl)butan-2-one
CAS No.
117896-99-8
Chemical Name
1,1,1-trifluoro-4-(4-hydroxyphenyl)butan-2-one
Synonyms
3-METHYL-2-OXOPENTANAL;1,1,1-trifluoro-4-(4-hydroxyphenyl)butan-2-one;2-Butanone, 1,1,1-trifluoro-4-(4-hydroxyphenyl)-
CBNumber
CB41359189
Molecular Formula
C10H9F3O2
Formula Weight
218.17
MOL File
117896-99-8.mol
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1,1,1-trifluoro-4-(4-hydroxyphenyl)butan-2-one Property

Boiling point:
272.5±35.0 °C(Predicted)
Density 
1.304±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
9.85±0.15(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Ambeed
Product number
A419314
Product name
1,1,1-Trifluoro-4-(4-hydroxyphenyl)butan-2-one
Purity
97%
Packaging
100mg
Price
$74
Updated
2021/12/16
Ambeed
Product number
A419314
Product name
1,1,1-Trifluoro-4-(4-hydroxyphenyl)butan-2-one
Purity
97%
Packaging
250mg
Price
$137
Updated
2021/12/16
Alichem
Product number
117896998
Product name
1,1,1-Trifluoro-4-(4-hydroxyphenyl)butan-2-one
Packaging
250mg
Price
$291.5
Updated
2021/12/16
Ambeed
Product number
A419314
Product name
1,1,1-Trifluoro-4-(4-hydroxyphenyl)butan-2-one
Purity
97%
Packaging
1g
Price
$307
Updated
2021/12/16
Crysdot
Product number
CD12176049
Product name
1,1,1-Trifluoro-4-(4-hydroxyphenyl)butan-2-one
Purity
97%
Packaging
1g
Price
$344
Updated
2021/12/16
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1,1,1-trifluoro-4-(4-hydroxyphenyl)butan-2-one Chemical Properties,Usage,Production

Synthesis

221915-87-3

117896-99-8

1. Boron tribromide (53 ml, 0.561 mol) was added dropwise to a dichloromethane solution (500 ml) of 1,1,1-trifluoro-4-(4-methoxyphenyl)butan-2-one (43.5 g, 0.187 mol) at -78 °C. 2. The reaction mixture was transferred to a 0°C ice bath and stirring was continued for 3 hours. 3. Ice water (200 ml) was added slowly and dropwise over 1 hr to quench the reaction. 4. The aqueous phase was saturated with solid sodium chloride and extracted with dichloromethane (500 ml) and ether (500 ml) respectively. 5. The organic layers were combined and dried with anhydrous magnesium sulfate and subsequently concentrated under vacuum. 6. Purification of the residue by ball-ball distillation (96-100 °C, 0.2 mmHg) afforded 1,1,1-trifluoro-4-(4-hydroxyphenyl)butan-2-one (34.4 g, 84%) as a yellow liquid, which solidified on standing. 7. Elemental analysis results (C10H9F3O2-0.5H2O): calculated value C 52.87%, H 4.44%; measured value C 52.93%, H 4.53%.

References

[1] Patent: US6350892, 2002, B1
[2] Patent: US6255496, 2001, B1
[3] Chemical Science, 2018, vol. 9, # 30, p. 6340 - 6347
[4] Analytical Chemistry, 2018, vol. 90, # 15, p. 9301 - 9307

1,1,1-trifluoro-4-(4-hydroxyphenyl)butan-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

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1,1,1-trifluoro-4-(4-hydroxyphenyl)butan-2-one Suppliers

China 25 India 1 United States 2 Global 28
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View Lastest Price from 1,1,1-trifluoro-4-(4-hydroxyphenyl)butan-2-one manufacturers

Career Henan Chemical Co
Product
1,1,1-trifluoro-4-(4-hydroxyphenyl)butan-2-one 117896-99-8
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1lg; 2kg; 5kg; 10kg; 100kg
Release date
2019-08-31

117896-99-8, 1,1,1-trifluoro-4-(4-hydroxyphenyl)butan-2-oneRelated Search:

tert-Butyl methyl ether

  • 1,1,1-trifluoro-4-(4-hydroxyphenyl)butan-2-one
  • 3-METHYL-2-OXOPENTANAL
  • 2-Butanone, 1,1,1-trifluoro-4-(4-hydroxyphenyl)-
  • 117896-99-8