ChemicalBook > CAS DataBase List > hippeastrine
hippeastrine
- Product Name
- hippeastrine
- CAS No.
- 477-17-8
- Chemical Name
- hippeastrine
- Synonyms
- Trispherine;hippeastrine;5α-Hydroxy-1-methyl-9,10-[methylenebis(oxy)]lycorenan-7-one;1-Methyl-5α-hydroxy-9,10-methylenedioxy-1,2,3,5aα,11bα,11cβ-hexahydro[2]benzopyrano[3,4-g]indole-7(5H)-one;[1,3]Dioxolo[6,7][2]benzopyrano[3,4-g]indol-7(1H)-one, 2,3,5,5a,12b,12c-hexahydro-5-hydroxy-1-methyl-, (5S,5aS,12bS,12cS)-
- CBNumber
- CB41370889
- Molecular Formula
- C17H17NO5
- Formula Weight
- 315.32
- MOL File
- 477-17-8.mol
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hippeastrine Property
- Melting point:
- 214-215 °C
- Boiling point:
- 539.3±50.0 °C(Predicted)
- Density
- 1.50±0.1 g/cm3(Predicted)
- pka
- 13.02±0.20(Predicted)
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hippeastrine Chemical Properties,Usage,Production
Uses
Hippeastrine, an active alkaloid, exhibits a good dose-dependent inhibitory effect against topoisomerase I (Top I) with an IC50 at 7.25?μg/mL. Antiproliferative and anticancer activities[1].
Definition
ChEBI: An indole alkaloid isolated from the Amaryllidaceae family and has been shown to exhibit cytotoxic activity.
References
[1] Chen GL, et al. Antiproliferative activities of Amaryllidaceae alkaloids from Lycoris radiata targeting DNA topoisomerase I. Sci Rep. 2016;6:38284. Published 2016 Dec 6. DOI:10.1038/srep38284
hippeastrine Preparation Products And Raw materials
Raw materials
Preparation Products
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hippeastrine Suppliers
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- 021-61312847; 18021002903
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- 18283602253; +8618283602253
- jancyzheng@gcgreenpure.com
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- China
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